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Reproductive Techniques

Code: 105062
Credits: 3
2026/2027
Degree programme Type Course
Genetics OP 4

Contact lecturer

Name :
Joan Blanco Rodriguez
Email :
joan.blanco@uab.cat

Teaching staff

Sergi Novo Bruña

Group languages

You can consult this information at the end of the document.

Prerequisites

In order to guarantee the achievement of the learning objectives, it is a prerequisite to have passed the subject "Genetics and Reproduction" in the third year of the degree.

Objectives

The subject of Reproductive Techniques aims to review the cellular and molecular mechanisms involved in mammalian reproduction, as well as the applications of gamete and embryo manipulation. Additionally, it will provide knowledge on assisted reproduction procedures in the realm of human and animal reproduction. In the final topics of the program, interventions on gametes and embryos related to new technologies will be addressed. The emerging new scenarios in this field, as well as the repercussions and impact of the resulting applications, will be explored.

Learning outcomes

  • CM31 (Propose solutions to diagnostic and assisted reproduction problems, evaluating their technical feasibility and ethical implications.) Propose solutions to diagnostic and assisted reproduction problems, evaluating their technical feasibility and ethical implications.
  • CM32 (Design strategies and projects in applied genetics considering technical resources and economic management.) Design strategies and projects in applied genetics considering technical resources and economic management.
  • KM24 (Describe the genetic basis of gametogenesis, embryonic development, and alterations in reproductive function.) Describe the genetic basis of gametogenesis, embryonic development, and alterations in reproductive function.
  • KM25 (Identify the bioethical and legal principles of applied genetics and genomic research, integrating the gender perspective.) Identify the bioethical and legal principles of applied genetics and genomic research, integrating the gender perspective.
  • SM28 (Apply genetic and genomic techniques for diagnostic analysis in the context of human reproduction.) Apply genetic and genomic techniques for diagnostic analysis in the context of human reproduction.
  • SM29 (Apply legal regulations and bioethical principles in genomic and reproductive practice.) Apply legal regulations and bioethical principles in genomic and reproductive practice.

Contents

Theory lessons

Topic 1. Fertilization and pre-implantation embryo development

Topic 2. Assisted reproduction techniques (ART) in humans

Topic 3. Assisted reproduction techniques (ART) in animals

Topic 4. Cryopreservation of gametes and embryos

Topic 5. Cloning

Topic 6. Genetic modification

Topic 7. Pluripotent cells and reproduction


Laboratory sessions

• In vitro culture and preimplantation embryo development

• Induction of oocyte maturation in vitro

• Embryo freezing

• Embryo manipulation: cloning by blastomere isolation

• Analysis of a semen sample

• Presentation and discussion of scientific articles


Learning activities and methodology

Title Hours ECTS Learning outcomes
Theoretical clases 15 0.6 KM24, KM25, SM28, SM29
Practice sessions 13 0.52 SM28
Study and self learning 32 1.28 CM31, CM32, KM24, KM25, SM28, SM29
Oral presentation 2 0.08 CM31, CM32, KM25, SM28, SM29
Tutorship 2 0.08 KM24, KM25
Preparation oral presentations 4 0.16 CM31, CM32, KM25, SM28, SM29

The subject consists of theoretical classes, practical classes, and bibliographic seminars. The organization and teaching methodology followed in the training activities are described below.

Theory Classes

The content of the theory program will be explained by the teacher through lectures, supported by audiovisual aids, and with active student participation encouraged through reciprocal questions. The tables, figures, and graphs used in class will be available in PDF format on the Virtual Campus. Students can also access videos, animations, and links to websites related to the subject on the Virtual Campus. In order to consolidate and clarify the content explained in class, students should regularly consult the books and review articles selected by the professor. The articles will be available in PDF format on the virtual campus.

Laboratory Practices

The practical classes are designed to learn the basic methodologies used and complement the theoretical training.

Students will work in groups of 2 and, during the practical sessions, they will have to answer a questionnaire.

Attendance to all practical classes is mandatory in order to pass the subject.

Bibliographic Seminars

Students will have to present an article published in an international scientific journal in the field of reproductive technologies. These sessions aim to deepen the knowledge imparted in the lectures, introduce topics of special interest, and foster a critical view of research results.

The articles will be distributed at the beginning of the teaching period for the subject. Each pair or group will present the assigned article for 5-8 minutes (depending on the number of enrolled students and the availability of time). The objective of this presentation is to provide an understandable summary of the objectives and results of the research article, draw conclusions, and encourage critical discussion.

Tutoring

Tutorials will be conducted upon request by students to address doubts regarding the theory and practical content.

Annotation: within the schedule set by the centre or degree programme, 15 minutes of one class will be reserved for students to evaluate their lecturers and their courses or modules through questionnaires.

Assessment

Continuous assessment activities

Title Weight Hours ECTS Learning outcomes
Examination of theoretical sessions 50 2 0.08 CM31, CM32, KM24, KM25, SM28, SM29
Oral presentation of papers 10 2 0.08 CM31, CM32, KM25, SM28, SM29
Evaluation of laboratory sessions 40 3 0.12 CM31, SM28

Assessment system

To pass the course, students must obtain a final grade equal to or higher than 5 out of 10, calculated according to the weighting of the different assessment activities. In addition, students must obtain a minimum grade of 4 out of 10 in the final theory examination.

Students who do not meet these requirements may take a resit examination. The characteristics of this examination will be equivalent to those established for the final examination.

Students who have passed the course may also take the resit examination in order to improve their theoretical component grade. In this case, the grade obtained in the resit examination will replace the previous grade, whether it is higher or lower.

To be eligible for the resit examination, students must have participated in assessment activities representing at least 67% of the total course grade; otherwise, they will be classified as Not assessable.

This course does not include a single assessment option.


Assessment activities

  1. Theoretical content examination: This will account for 50% of the final course grade. The entire syllabus covered in the theory classes will be assessed. The examination will consist of a multiple-choice test. In order for the grade obtained to be included in the calculation of the final course grade, students must obtain a mark higher than 4 out of 10 in this examination.
  2. Assessment of practical sessions: This will account for 40% of the final course grade and attendance is compulsory. Laboratory practical sessions will be assessed during their completion through the answers provided in the corresponding questionnaires, in order to determine whether the competencies and learning objectives have been achieved. Students’ attitude and performance will also be assessed.
  3. Assessment of oral presentations: This will account for 10% of the final course grade. The submitted work and the oral presentation will be assessed.


Irregularities in assessment activities

Any irregularity in an assessment activity (academic misconduct, plagiarism, or improper use of artificial intelligence tools, except when such use is expressly authorised by the teaching staff) that may significantly affect the evaluation of the activity will result in a grade of 0 for that activity.

In this course, the use of electronic devices with access to artificial intelligence tools is not permitted during any assessed activity. Any breach of this rule will be considered an assessment irregularity.

If multiple irregularities are detected in different assessment activities, the final course grade will be 0. Without prejudice to this, the teaching staff may initiate the corresponding disciplinary procedure in accordance with current regulations.

Bibliography

Genral information of the topics coould be found in the following texbooks
 

Bajo JM, B. Coroleu B. (Eds.) Fundamentos de Reproducción. Editorial Panamericana. Madrid. 2009.

Elder K., Dale B. In vitro fertilization. (3rd edition). Cambridge University Press. New York. 2011.

Fauser B.C.J.M. (Ed.). Molecular Biology in Reproductive Medicine. The Parthenon Publishing Group. New York. 1999

Gardner D.K. et al. (Eds.). Textbook of assisted Reproductive Techniques. Martin Dunitz Pub. Hampshire. 2001.

Gupta S.K. et al. (Eds.) Gamete Biology. Emerging frontiers in Fertility and Contraceptive Development.

Nottingham University Press. Nottingham. 2007.

Hafez B. and Hafez E.S.E. (Eds.). Reproduction in farm animals. 7th edition. Lippincott Williams and Wilkins. USA. 2000.

Harper J. (Ed.) Preimplantation Genetic Diagnosis. (2nd Edition). Cambridge University Press. New York

(USA).2009.

Johnson M.H. and Everitt B.J. (Eds.) Essential Reproduction. 5th Edition. Blackwell Science. Oxford. 2005.

Lanza R. Et al. (Eds.) Handbook of Stem Cells. Vol 1 i 2. Elsevier Academic Press. Amsterdam. 2004.

Matorras R, Hernández J. (Eds.). Estudio y tratamiento de la pareja estéril. Adalia. Madrid. 2007.

Nadal J. (Ed.). Donación de ovocitos. Momento Médico Iberoamericana. Madrid. 2010.

Remohí J., Pellicer A., Simón C., Navarro J. (Eds.). Reproducción Humana. 2ª Edición. McGraw

Hill-Interamericana. Madrid. 2002.

Wolf D.P. and Zelinski-Wooten M. (Eds.). Assisted fertilization and nuclear transfer in mammals. Humana Press. New Jersey. USA. 2001.

During thecourse, specific bibliography will be recommended for the preparation of sections of the syllabus by the students.

Reviews and updated papers will be also recommended.
Web links containing rigorous and up-to-date information will be suggested.

Software

Not appplicable

Course groups and languages

The information provided is provisional until November 30. After this date, you will be able to consult the language of each group through this link. To access the information, you will need to enter the course CODE

Type of teaching Group Language Semester Shift
(TE) Theory 64 Catalan/Spanish second semester morning-mixed
(PLAB) Practical laboratories 641 Catalan/Spanish second semester afternoon
(PLABs) Suport a les pràctiques de laboratori 641 Catalan/Spanish second semester afternoon
(PLAB) Practical laboratories 642 Catalan/Spanish second semester afternoon
(PLABs) Suport a les pràctiques de laboratori 642 Catalan/Spanish second semester afternoon