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Progress in the Neurobiology of Communication and Language

Code: 45529
Credits: 6
2026/2027
Degree programme Type Course
Communication and Language Disorders OB 1

Contact lecturer

Name :
Margalida Coll Andreu
Email :
margalida.coll@uab.cat

Teaching staff

Margalida Coll Andreu
Sonia Darbra Marges

Group languages

You can consult this information at the end of the document.

Prerequisites

No prerequisites are needed.

Objectives

The objective of the subject is to provide current knowledge to students about functional neuroanatomy and neurochemistry of communication and language disorders. The students will work on questions that require understanding the nature of the genetic and epigenetic mechanisms of various disorders and analyzing the importance of the relationship between the genetic factors and the protective and risk environmental factors. Furthermore, it is intended that students understand the characteristics of of brain development throughout the life span and experience-dependent functional reorganization of the brain. The students will also acquire skills and competences related to the critical reading of scientific publications and to the communication of information about the neurobiology of communication and language.

Learning outcomes

  • CA02 (Critically analyse research data in the neurobiology of communication and language disorders.) Critically analyse research data in the neurobiology of communication and language disorders.
  • CA03 (Clearly communicate information about the neurobiology of communication and language disorders to the specialist public and the general public.) Clearly communicate information about the neurobiology of communication and language disorders to the specialist public and the general public.
  • CA04 (Make decisions autonomously in the context of the neurobiology of communication and language.) Make decisions autonomously in the context of the neurobiology of communication and language.
  • KA04 (Distinguish between the relevance and adequacy of research methods and designs in the context of the neurobiology of communication and language disorders.) Distinguish between the relevance and adequacy of research methods and designs in the context of the neurobiology of communication and language disorders.
  • KA05 (Scientifically analyse the limitations and biases of theories in the field of neurobiology of communication and language disorders.) Scientifically analyse the limitations and biases of theories in the field of neurobiology of communication and language disorders.
  • SA04 (Critically interpret scientific publications in the field of neurobiology of language and communication.) Critically interpret scientific publications in the field of neurobiology of language and communication.
  • SA05 (Write scientific reports in the field of neurobiology of communication and language disorders.) Write scientific reports in the field of neurobiology of communication and language disorders.
  • SA06 (Use documentary sources to obtain relevant information in the field of neurobiology of communication and language.) Use documentary sources to obtain relevant information in the field of neurobiology of communication and language.

Contents

• Functional Neuroanatomy of Language and Communication

• Genes, Language and Communication

• Brain Development and Plasticity

• Neurochemical Alterations in Language and Communication Disorders

Learning activities and methodology

Title Hours ECTS Learning outcomes
Reading articles and other scientific documents 40.5 1.62 CA02, KA04, SA04, SA06
Search for documentation in journals, books and other documentation sources 8 0.32 CA02, SA04, SA06
Personal study 40.5 1.62 CA02, KA04, KA05, SA04, SA06
Tutorial 7.5 0.3
Preparation of oral presentation 7 0.28 CA03, CA04
Preparation of written works 15 0.6 CA02, CA03, CA04, KA04, KA05, SA04, SA05, SA06
Expository classes 30 1.2 CA02, KA04, KA05, SA04, SA06
Oral presentations 1.5 0.06 CA03, CA04
The teaching methodology is based on different activities. Depending on the situation, active
lectures or seminars will be held and supervised independent activities will be carried out:Use of artificial intelligence:
In this subject, the use of Artificial Intelligence (AI) technologies is allowed as an integral part
of the development of the work, provided that the final result reflects a significant contribution
of the student in the analysis and personal reflection. The student must clearly identify which parts
have been generated with this technology, specify the tools used and include a critical consideration on
how these have influenced the process and the final result of the activity. The lack of transparency
in the use of AI will be considered a lack of academic honesty and may lead to a penalization in the
grade of the activity, or greater sanctions in serious cases.
Annotation: within the schedule set by the centre or degree programme, 15 minutes of one class will be reserved for students to evaluate their lecturers and their courses or modules through questionnaires.

Assessment

Continuous assessment activities

Title Weight Hours ECTS Learning outcomes
EV1: Critical analysis of bibliographic sources 25 0 0 CA02, KA04, KA05, SA04
EV2a: Bibliographic search results 15 0 0 CA02, CA04, SA04, SA06
EV3: Oral presentation and defense of the revision work 30 0 0 CA03, CA04
EV2b: Written review work (maximum 5 pages) 30 0 0 CA02, CA03, CA04, KA04, KA05, SA04, SA05, SA06


The evaluation of the subject will be carried out following the \"Evaluation Guidelines for the Degrees of the Faculty of Psychology\", which can be found at https://www.uab.cat/web/estudiar/graus/graus/avaluacions-1345722525858.html, and based on various evidence of learning:

EV1: Critical analysis of scientific bibliographic sources (25% of the final grade). Written and in group. Submission: week 7. Feedback: week 8 in a specific rubric format.

EV2: Dissertation about a relevant issue on the Neurobiology of Hearing, Language and Communication (40% of the final grade): Written and Individual.

EV2a: Results of the bibliographic search (4 articles) (10%) Submission: Week 9. This evidence may require more than one feedback, depending on the initial selection of papers. The first feedback will be done on week 9. If required, a second feedback will be done on week 10 in written format.

EV2b: Preparation and submission of a written report on the chosen topic about the Neurobiology of Hearing, Language and Communication (30%). Submission: week 15. Feedback on week 19 in a tutorial format.

EV3 Oral presentation and defense of the chosen topic (30%). Feedback on week 19 in a tutorial format


Overall grade

The overall grade for the subject will be the weighted average of the scores obtained in each of the learning evidences, provided that the grade of EV2b is equal to or greater than 4.

In the event that these requirements are not met, the grade on the academic transcript will be the lower value between 4.5 points and the weighted average of the grades of the continuous assessment.


Kind of feedback EVIDENCE WEEK
Written EV1 8
Written EV2a 9-10 (depending on whether changes in the initial selections have to be done after the first feedback)
Tutoring EV2b 20
Tutoring EV3 20




Recovery

Due to its nature, EV3 cannot be recovered.

If the final grade of the Module does not reach 5 and/or the EV2b grade is lower than 4, it will be necessary to recover. Recovery consists of re-elaborating EV2 (Ev2a and EV2b).

The maximum grade that can be obtained after recovery is 5 (out of 10).


Definition of \"Non evaluable\"

Students who have not submitted either of the two pieces of evidence related to the Review Work (EV2a and EV2b) or who have submitted several pieces of evidence but the total weight of these is less than 40.5 of the final grade will receive the grade of \"Non evaluable\"


Synthesis test

For students in their 2nd year or later, the same continuous assessment will be followed, therefore it is NOT expected that there will be an assessment through a single non-recoverable synthesis test.

Bibliography

BASIC BIBLIOGRAPHY

Bishop DV (2009)  Genes, cognition, and communication: insights from neurodevelopmental disorders. Ann N Y Acad Sci. 1156:1-18. 

Braid J, Richlan F (2022) The Functional Neuroanatomy of Reading Intervention. Front Neurosci. 16:921931

Caspi A; Moffitt TE (2006)  Gene-environment interactions in psychiatry: joining forces with neuroscience. Nat Rev Neurosci. 7(7): 583-590.

Gazerani P (2025) The neuroplastic brain: current breakthroughs and emerging frontiers. Brain Res. 1858:149643

Ghosh A, Michalon A, Lindemann L, Fontoura P, Santarelli L (2013) Drug discovery for autism spectrum disorder: challenges and opportunities. Nat Rev Drug Discov. 12(10):777-90

Local activity alterations in autism spectrum disorder correlate with neurotransmitter properties and ketamine induced brain changes

Kral A, Sharma A (2023) Crossmodal plasticity in hearing loss. Trends Neurosci. 46(5):377-393

Lieberman P (2013) Synapses, Language, and Being Human. Science. 342(6161):944-945

Manter MA, Birtwell KB, Bath J, Friedman NDB, Keary CJ, Neumeyer AM, Palumbo ML, Thom RP, Stonestreet E, Brooks H, Dakin K, Hooker JM, McDougle CJ (2025) Pharmacological treatment in autism: a proposal for guidelines on common co-occurring psychiatric symptoms. BMC Med. 23(1):11

Marotta R, Risoleo MC, Messina G, Parisi L, Carotenuto M, Vetri L, Roccella M (2020) The Neurochemistry of Autism. Brain Sci. 10(3):163

Montanari M, Martella G, Bonsi P, Meringolo M (2022) Autism Spectrum Disorder: Focus on Glutamatergic Neurotransmission. Int J Mol Sci. 23(7): 3861

Nasios G, Dardiotis E, Messinis L. (2019) From Broca and Wernicke to the Neuromodulation Era: Insights of Brain Language Networks for Neurorehabilitation. Behav Neurol. 2019:9894571

Newbury DF, Monaco AP, Paracchini S.(2014)  Reading and language disorders: the importance of both quantity and quality. Genes.  5(2):285-309.

Norton ES,  Beach SD, Gabrieli JD (2015) Neurobiology of dyslexia. Current Opinion in Neurobiology, 30: 73-38.

Poeppel D (2014) The neuroanatomic and neurophysiological infrastructure for speech and language. Current Opinion in Neurobiology, 28: 142-149.

Purves D, Augustine GJ, Fitzpatrick D, Hall WC, Lamantia A-S, Mcnamara JO, Williams, S. Neurociencia (3ª Ed, 2007). Buenos Aires: Editorial Médica Panamericana. Capítulos 21, 22, 23 y 24

Simmons, D (2008) Behavioral genomics. Nature Education 1(1):54.

Tomiyama S, Yoshida K, Tani H, Uchida H (2025) Pharmacological Treatment of Autism Spectrum Disorder: A Systematic Review of Treatment Guidelines. Pharmacopsychiatry 58(3):100-116

Wolpaw JR, Thompson AK (2023) Enhancing neurorehabilitation by targeting beneficial plasticity. Front Rehabil Sci. 4:1198679

 

COMPLEMENTARY BIBLIOGRAPHY

Bates E, Roe K (2001) Language development in children with unilateral brain injury. En: Nelson, C. A.; Luciana, M. (Eds). Handbook of developmental Cognitive Neuroscience. The MIT Press. Pp. 281-308.

Bavelier D, Neville HJ (2002) Cross-modal plasticity: Where and how? Nature Reviews Neuroscience, 3: 443-452

Canitano R (2014) New experimental treatments for core social domain in autism spectrum disorders. Front Pediatr. 2:61

Dror, AA, Avraham KB. (2009) Hearing loss: Mechanisms revealed by genetics and cell biology. Annu. Rev. Genet. 43: 411-437

Hagoort P. (2017). The core and beyond in the language-ready brain. Neurosci Biobehav Rev.; 81(Pt B):194-204.

Heimler B, Weisz N, Collignon O (2014) Revisiting the adaptive and maladaptive effects of crossmodal plasticity. Neuroscience, 283: 44-63. 

Kleim, J. A. & Jones, T. A. (2008). Principles of experience-dependent neural plasticity: implications for rehabilitation after brain damage. Journal of Speech, Language, and Hearing Research, 51, 225-239.

Kral A, Sharma A (2012) Developmental neuroplasticity after cochlear implantation. Trends in Neurosciences, 35(2):  111-122.

Marcus G, Rabagliati H (2006) What developmental disorders can tell us about the nature and origins of language. Nat Neurosci. 9(10): 1226-1229. 

Matsunaga E, Okanoya K (2014) Cadherins: potential regulators in the faculty of language. Curr Opin Neurobiol, 28:28-33

Narbona, J. & Crespo-Eguílaz, N. (2012). Plasticidad cerebral para el lenguaje en el niño y el adolescente. Revista de Neurología, 54 (Supl. 1), 127-130.

Small SL, Llano DA (2009) Biological approaches to aphasia treatment. Curr Neurol Neurosci Rep. 9(6):443-50

Spooren W, Lindemann L, Ghosh A, Santarelli L (2012) Synapse dysfunction in autism: a molecular medicine approach to drug discovery in neurodevelopmental disorders. Trends Pharmacol Sci. 33(12):669-84 

White EJ, Hutka SA,  Williams LJ, Moreno S (2013) Learning, neural plasticity and sensitive periods: implications for language acquisition, music training and transfer across the life span. Frontiers in Systems Neuroscience, 7, Article 90 

Wong PC, Morgan-Short K, Ettlinger M, Zheng J (2012) Linking neurogenetics and individual differences in language learning: the dopamine hypothesis. Cortex 48(9):1091-10

Software

Search Engine (Edge, Google, ...)

Text Editor (Word, ...)

Presentation Designer (PowerPoint, ...)

Online Teaching (Teams, ...)

UAB Virtual Campus (Moodle): Basic communication tool and material repository.

Course groups and languages

The information provided is provisional until November 30. After this date, you will be able to consult the language of each group through this link. To access the information, you will need to enter the course CODE

Type of teaching Group Language Semester Shift
(TEm) Theory (master) 1 Catalan/Spanish first semester afternoon