Analytical Chemistry
Code: 106810Credits: 6
| Degree programme | Type | Course |
|---|---|---|
| Nanoscience and Nanotechnology | OB | 3 |
Contact lecturer
- Name :
- Maria del Mar Puyol Bosch
- Email :
- mariadelmar.puyol@uab.cat
Group languages
You can consult this information at the end of the document.
Prerequisites
To have completed the subject of Chemical Reactivity, 1st year Degree in Nanoscience and Nanotechnology
Objectives
In this subject the basic knowledge of Analytical Chemistry and Chemical Analysis must be acquired. The main objective is to establish the concepts and methodologies of work, so that the student can apply them in real practical cases. Some examples of application in the field of analytical nanosystems will be mentioned.
The subject is structured in five blocks of homogeneous content but of different duration.
Block 1: The objective of Analytical Chemistry, the analytical process and, above all, the different calibration methods are introduced, as well as basic statistics for its correct use and interpretation of results.
Block 2: Introduction to chromatography. Basic principles; gas chromatography; high resolution liquid chromatography.
Block 3: Brief introduction to the classical methods of wet analysis.
Block 4: Introduction to analytical spectroscopy. Special emphasis will be placed on molecular analysis techniques and the most common atomic analysis techniques will be introduced. The principles and applications of infrared spectroscopy will be described as an example of qualitative analysis.
Block 5: Introduction to electrochemical analysis, especially potentiometric methods and the basic principles of amperometry.
Learning outcomes
- CM13 (Apply chemical knowledge to solve quantitative and qualitative problems, using bibliographic sources when necessary.) Apply chemical knowledge to solve quantitative and qualitative problems, using bibliographic sources when necessary.
- CM14 (Work collaboratively to plan and organise the basic tasks carried out in a physicochemical analysis laboratory.) Work collaboratively to plan and organise the basic tasks carried out in a physicochemical analysis laboratory.
- CM15 (Handle chemical products and wastes while taking their impact on safety and the environment into account.) Handle chemical products and wastes while taking their impact on safety and the environment into account.
- KM23 (Identify the analysis methods and cite the different stages of analysis, as well as the analytical quality indicators.) Identify the analysis methods and cite the different stages of analysis, as well as the analytical quality indicators.
- SM21 (Apply the main techniques used in to identify and characterise the structure and composition of the material.) Apply the main techniques used in to identify and characterise the structure and composition of the material.
Contents
B1. Introduction and data processing
Unit 1. Objective of the Analytical Chemistry. Analytical process. Methods of analysis: classical methods and instrumental methods. Calibration protocols: external calibration, standard addition and internal standard.
Unit 2. Validation of an analytical method. Analytical quality parameters. Precision. Accuracy. Sensitivity. Selectivity. Detection limit and quantification limit.
Unit 3. Statistical evaluation of analytical data. Experimental error, uncertainty and significant figures. Significance tests: t and F. Univariable calibration methods: lineasr regression.
B2. Introduction to chromatography
Unit 4. Introduction. Classification of chromatographic techniques. Basic parameters.
Unit 5. Gas chromatography. Instrumentation. Types of columns. Stationary phases. Mass detector coupling. Application examples.
Unit 6. High resolution liquid chromatography. Instrumentation. Application examples
B3. Classical chemical analysis
Unit 7. Quantitativeness of a reaction. Conditional constants. Complexation volumes. Examples of applications.
Unit 8. Sampling. Sampling statistics. Ingamells equation. Sample preparation. Solid phase extraction (SPE).
B4. Introduction to analytical spectroscopy
Unit 9. Electromagnetic spectrum. Matter radiation interaction. Classification of spectroscopic techniques. Beer-Lambert's law.
Unit 10. Molecular spectroscopy. Classification. UV-Vis spectrophotometry. Luminescence. Optical sensors. Immunoassays. Infrared spectroscopy: application to qualitative analysis.
Unit 11. Atomic spectroscopy. Classification. Atomic absorption spectroscopy. Emission spectroscopy: flame and ICP.
B5. Introduction to electrochemical analysis:
Unit 12. Potentiometry. Indicator electrodes. Reference electrodes. Selective electrodes. Sensors and biosensors.
Unit 13. Amperometry. Polarography. Basic concept of the amperometric curves. Example of amperometry: blood glucose control.
Learning activities and methodology
| Title | Hours | ECTS | Learning outcomes |
|---|---|---|---|
| study | 52 | 2.08 | CM13, KM23, SM21 |
| Resolution of numerical exercices | 24 | 0.96 | CM13, KM23, SM21 |
| Laboratory practices | 12 | 0.48 | CM14, CM15 |
| Tutorials | 4 | 0.16 | CM13, KM23, SM21 |
| resolution of numerical exercises | 10 | 0.4 | CM13, KM23, SM21 |
| Complementary works (audiovisual or reports) | 3 | 0.12 | CM13, KM23, SM21 |
| Theory classes | 30 | 1.2 | KM23, SM21 |
| Bibliographic search | 4 | 0.16 | CM13 |
The student will carry out three types of activities: directed, autonomous and supervised.
1. Supervised activities: Attendance is compulsory and is carried out in the presence of a teacher.
1. Theoretical classes: The teacher explains the contents of the subject and answers any questions that the student may have.
2. Problems solving: The knowledge acquired in the master classes and in the autonomous activities of the student, mainly through the study, are applied to the resolution of problems and exercises related to the contents of the subject.
3. Laboratory practices: They involve the performance of practical work related to the contents of the subject.
2. Autonomous activities: With these activities the student alone, or in group, has to achieve the own competences of the asignatura. These activities include study, problem solving, text reading and bibliography research.
3. Supervised activities: The student can request tutorials of support for the assimilation of the matter exposed in the classes of theory, problems and practices.
Assessment
Continuous assessment activities
| Title | Weight | Hours | ECTS | Learning outcomes |
|---|---|---|---|---|
| Pre-lab Tests | 7.5% | 0.5 | 0.02 | CM13, CM15, KM23, SM21 |
| Laboratory practices reports | 15% | 3 | 0.12 | CM13, CM14, CM15, KM23, SM21 |
| Report HPLC Simulation | 7.5% | 1.5 | 0.06 | CM13, SM21 |
| 1st part exam | 35% | 3 | 0.12 | CM13, KM23, SM21 |
| 2on part exam | 35% | 3 | 0.12 | CM13, KM23, SM21 |
A) Continuous assessment
1. Written theory exams: Two midterm exams will be held throughout the course, one in the middle and the other at the end of the semester. Each of these exams will have a weight of 35% of the final grade.
- First midterm: The contents of Topics 1 to 6 will be evaluated (35% of the final grade)
- Second midterm: The contents of Topics 7 to 12 will be evaluated (35% of the final grade)
2. Laboratory practices: Laboratory practices will be evaluated through the correction of practice reports, simulations and pre-lab tests, each of these parts has the following weight in the final grade:
Pre-lab tests (7.5%): before starting an experimental laboratory practice, a test will be carried out with the content of the practice guide.
Internship reports (15%). Preparation of three practices reports.
Simulation (7.5%): delivery of simulation study results of a separation of a test sample by HPLC.
Attendance at laboratory practices is mandatory. In the event of non-compliance with the safety regulations, a student may be expelled from the laboratory and suspend the practice of this day. In the event of serious or repeated non-compliance with the safety rules, he/she may be expelled from the laboratory, and the subject may be suspended.
This can note be repeated/retaken.
The final grade will be obtained as:
Final grade = Grade of written exams (70%) + Grade of reports of practices and pre-labs (22.5%) + Grade Simulation (7.5%)
In order to pass the subject, it is necessary to meet these conditions:
1) The grade of each of the written theory exams must be ≥ to 4.0.
2) The average grade of the two written theory exams must be ≥ to 5.0.
3) The weighted average grade for all the assessment activities of the subject must be ≥ to 5.0.
4) Have attended the laboratory practices
Students who do not meet conditions 1 and/or 2 must take a retake exam at the end of the semester, which will be independent for each of the two parts of the course. The grade obtained in this retake exam will replace that of the corresponding previous written exams. To take these exams, students must have participated in evaluation activities throughout the course that are equivalent to 2/3 of the grade of the subject. Otherwise, the grade will be "Not assessed".
If after the retake exam, the student does not meet conditions 1 and/or 2, the maximum grade they can obtain will be 4.8, Failed.
B) Single evaluation:
Written theory exam: A single theory/problems exam will be carried out that will have a weight of 77.5% on the final grade. This final exam will be divided into two parts, each of which will be assessed separately with a weight of 38.75%.
Laboratory practices: The reports of the laboratory practices (15%), and the grades of the pre-lab tests (7.5%) will be considered.
The final grade will be obtained as:
Final grade = Grade of the written exam (77.5%) + Grade of the laboratory practices (22.5%).
To pass the subject, it is necessary to meet these conditions:
1) The grade of each of the two independent parts of the written theory exam must be ≥ to 4.0.
2) The average grade of the two written theory exams must be ≥ to 5.0.
3) The weighted average grade for all the assessment activities of the subject must be ≥ to 5.0.
4) Have attended the internship
Students who do not meet conditions 1 and/or 2 must take a retake exam later, which will be independent for each of the two parts of the course. The grade obtained in this retake exam will replace that of the parts of the previous written exam that had to be retaken. To take the retake exam, students must have previously participated in the activities of the single assessment. Otherwise, the grade will be "Not assessed".
If after the retake exam, the student does not meet conditions 1 and/or 2, the maximum grade they can obtain will be 4.8, failed.
Use of artificial intelligence:
Restricted use - For this subject, the use of Artificial Intelligence (AI) technologies is allowed exclusively in support tasks, such as bibliographic or information search, or translations. The student should clearly identify which parts have been generated with this technology, specify the tools used, and include critical reflection on how these have influenced the process and the outcome of the activity. The non-transparency of the use of AI in this assessable activity will be considered academic dishonesty and may lead to a partial or total penalty in the grade of the activity, or greater sanctions in cases of severity.
Fraud, plagiarism, and AI misuse
The performance of any irregularity in an assessment act (academic fraud, plagiarism or improper use of AI, unless this use is expressly authorised in this teaching guide) that may lead to a significant variation in the grade, means that this act will be graded with a 0. If this activity is a requirement to pass the subject, or that there are various irregularities in different assessment activities of the same subject, the final grade of the subject will be 0. Apart from the academic consequences described above, the University may initiate the disciplinary procedures provided for by current regulations.
Bibliography
Harris, D. C.; Lucy, C. A. Quantitative Chemical Analysis. 10th ed. Macmillan Learning, Boston, 2020. ISBN: 978-1319324506. Versión en español: Harris, D. C. Análisis químico cuantitativo. 3.ª ed. (traducción de la 6.ª ed. original). Editorial Reverté, Barcelona, 2012. ISBN: 978-84-291-7224-9.
Skoog, D. A.; West, D. M.; Holler, F. J.; Crouch, S. R. Fundamentals of Analytical Chemistry. 10th ed. Cengage Learning, Boston, 2022. ISBN: 978-0357450390.
Skoog, D. A.; Holler, F. J.; Crouch, S. R. Principles of Instrumental Analysis. 7th ed. Cengage Learning, 2018. Versión en español: Principios de análisis instrumental. Editorial Cengage Learning.
Kellner, R.; Mermet, J. M.; Otto, M.; Valcárcel, M.; Widmer, H. M. Analytical Chemistry. Wiley-VCH, Weinheim
Software
To activate the Excel Complement: Data Analysis
Course groups and languages
The information provided is provisional until November 30. After this date, you will be able to consult the language of each group through this link. To access the information, you will need to enter the course CODE
| Type of teaching | Group | Language | Semester | Shift |
|---|---|---|---|---|
| (TE) Theory | 1 | Catalan | second semester | afternoon |
| (PAUL) Classroom practices | 1 | Catalan/Spanish | second semester | afternoon |
| (PLAB) Practical laboratories | 1 | Catalan | second semester | morning-mixed |
| (PLABs) Suport a les pràctiques de laboratori | 1 | Catalan/Spanish | second semester | morning-mixed |
| (PLAB) Practical laboratories | 2 | Catalan | second semester | morning-mixed |
| (PLABs) Suport a les pràctiques de laboratori | 2 | Catalan/Spanish | second semester | morning-mixed |
| (PLAB) Practical laboratories | 3 | Catalan | second semester | morning-mixed |
| (PLABs) Suport a les pràctiques de laboratori | 3 | Catalan/Spanish | second semester | morning-mixed |