
Cell Biology
Code: 101914Credits: 6
| Degree programme | Type | Course |
|---|---|---|
| Biomedical Sciences | FB | 1 |
Contact lecturer
- Name :
- Ester Anton Martorell
- Email :
- ester.anton@uab.cat
Teaching staff
- Irene Fernandez Duran
Group languages
You can consult this information at the end of the document.
Prerequisites
Since Cell Biology is a first-semester subject of the Bachelor's Degree in Biomedical Sciences, there are no prerequisites for taking it. However, it is recommended that students have previous knowledge of basic biology, so that they can follow the classes. This would mostly include general aspects of cell structures and their organic composition (proteins, nucleic acids, carbohydrates, and lipids), as well as the main cellular metabolic pathways.
In addition, since most scientific information sources are in English, it is advisable to have a good grounding in this language.
Objectives
Cell Biology is a basic subject of the Bachelor's Degree in Biomedical Sciences at the Autonomous University of Barcelona. The course aims to establish sound knowledge of the structural organization, functioning and regulation of eukaryotic cells. These contents will be complemented by those of other basic and compulsory subjects within the Biomedical Sciences study plan, like Medical Genetics, Histology and General Physiology, and Molecular Cell Biology. Together, these subjects will provide a good understanding of the structural and functional organization of living organisms.
The theoretical contents corresponding to this subject will be complemented by practical laboratory training in the subject “Laboratory I” which integrates the practical content of all first-year subjects included in this Bachelor’s Degree (for more information, see the corresponding Study Guide).
The following are the specific training goals of the subject Cell Biology:
- To recognize the main differences between prokaryotes and eukaryotes.
- To describe the structure, composition, and main features of cell membranes.
- To explain the organization and composition of other elements of the cell surface.
- To describe the transport processes through cell membranes.
- To describe the structure, composition, and function of the different compartments of eukaryotic cells, as well as the relationships between them.
- To explain the role of mitochondria in cell bioenergetics.
- To describe the protein classification systems and their intracellular distribution pathways.
- To describe chromatin composition and its organization throughout the cell cycle.
- To list the cytoskeleton elements and describe their composition and structure.
- To explain the contribution of the cytoskeleton to the cell shape and movement.
- To identify and describe molecules, structures and processes involved in a cell’s communication with the external environment and other cells.
- To identify molecules involved in cell cycle regulation and explain their role.
- To list and describe the different mitotic and meiotic phases and to compare both types of cell divisions.
- To relate the functioning of eukaryotic cells with the occurrence of some diseases.
- To integrate and apply knowledge of theory when interpreting and resolving basic cell biology experiments.
- To use the appropriate scientific terminology in the field of cell biology.
Learning outcomes
- CM07 (Draw on information on the functions of different organelles and cellular structures to solve complex problems related to cell functioning in biological and biomedical contexts.) Draw on information on the functions of different organelles and cellular structures to solve complex problems related to cell functioning in biological and biomedical contexts.
- KM06 (Describe cell structure, functioning, and regulation of the cell cycle and reproduction.) Describe cell structure, functioning, and regulation of the cell cycle and reproduction.
- SM07 (Interpret the results of cell biology and genetics experiments.) Interpret the results of cell biology and genetics experiments.
Contents
The contents of this subject will include the following points:
BLOCK I-INTRODUCTION
Unit 1. Organization of prokaryotic and eukaryotic cell.
BLOCK II- CELL SURFACE
Unit 2. Structure and composition of the plasma membrane.
Unit 3. Transport of molecules through the membrane.
Unit 4. Extracellular matrix and cell wall.
Unit 5. Unions and cell adhesion.
BLOCK III- CYTOSKELETON
Unit 6. Microfilaments.
Unit 7. Microtubules.
Unit 8. Intermediate filaments.
BLOKC IV- INTRACEL·LULAR COMPARTMENTS
Unit 9. Introduction to the intracellular compartments and protein sorting.
Unit 10. Nucleus.
Unit 11. Cytosol.
Unit 12. Introduction to the endomembrane system. Endoplasmic reticulum.
Unit 13. Golgi apparatus. Basics of vesicular transport.
Unit 14. Endosomes, lysosomes, and vacuoles.
Unit 15. Mitochondria.
Unit 16. Peroxisomes.
BLOCK V- CELLULAR REGULATION
Unit 17. Cell signaling.
Unit 18. Cell cycle.
Unit 19. Mitosis.
Unit 20. Meiosis.
Learning activities and methodology
| Title | Hours | ECTS | Learning outcomes |
|---|---|---|---|
| Self-learning work | 10 | 0.4 | CM07 |
| Problem resolution work in groups | 32 | 1.28 | SM07 |
| Theory classes | 36 | 1.44 | KM06 |
| Individual study | 59.5 | 2.38 | CM07, KM06, SM07 |
| Problem-based classes | 9 | 0.36 | CM07, SM07 |
The subject of Cell Biology includes Theory classes and Problem-based classes. Below, the organization and teaching methodology for these two types of training activities are described.
Theory classes
The content of the Theory program will be taught mainly in the form of formal lectures with audio-visual support. This will include PowerPoint presentations containing an index for each unit with the most important points that will be described, illustrative schematics of the contents, and also images of cells or their components, to familiarize students with real cell structure and organization. The teacher will make supplementary audio-visual material available to the students through the Moodle classroom of the subject, to help them follow the lectures. They are recommended to bring this material to class as a support when taking notes. Some animations and videos related to cellular processes described in specific units will also be displayed.
Students will be advised to consult the recommended books listed in the Bibliography section of this Study Guide on a regular basis, in order to consolidate and, if necessary, clarify the contents described. In addition, it will also be recommended that they consult the links made available through the Moodle classroom: to additional videos and animations that, due to time constraints or content prioritization, cannot be shown in class.
In addition to attending the lectures, some contents of the Theory syllabus must be addressed by students through complementary methodologies that require active participation and the development of transversal competences related to autonomous learning.
Specifically, students will be required to prepare selected topics from the Theory syllabus based on guidelines provided by the teaching staff. These guidelines will consist of a detailed outline for each topic, identifying the key concepts to be acquired and serving as a basis for structuring the material.
Furthermore, the teaching staff will propose an indicative schedule for the preparation of these topics and the resolution of related questions, in order to integrate these activities with the progression of the Theory syllabus and the Problem-based classes.
Problem-based classes
During these sessions, students will give presentations to the rest of the class, offering solutions to experimental problems related to the contents of the Theory program. In general, no additional content will be included in these sessions, as their main aim is to consolidate and facilitate comprehension of the contents presented in the Theory classes, and to familiarize students with interpreting scientific data and problem-solving through real experimental situations.
In these sessions, students will be organized into work teams and will present the solutions to the exercises they have previously worked on outside of class, as scheduled. At the beginning of the semester, the teacher will provide students with a dossier containing all the exercises to be worked on throughout the course, along with a calendar of presentations, via the Moodle classroom. Students must have previously submitted the detailed written solutions to these exercises in presentation format through the Virtual Campus (one submission per group, with the exercises corresponding to each session). During each session, the teacher will ask a member of a team to present the solution to a problem to the rest of the class, using the submitted presentation. The students selected to present will be chosen by the teacher, who will ensure that each student presents at least one exercise throughout the course. The teacher will evaluate the presentations, and the grade obtained will be the same for all membersof the group, regardless of who made the presentation.
Assessment
Continuous assessment activities
| Title | Weight | Hours | ECTS | Learning outcomes |
|---|---|---|---|---|
| First interim test | 40% | 1.5 | 0.06 | CM07, KM06 |
| Problem-solving exam (individual assessment) | 5% | 0.5 | 0.02 | CM07, SM07 |
| Problem-solving oral presentations (group assessment) | 15% | 0 | 0 | CM07, SM07 |
| Second interim test | 40% | 1.5 | 0.06 | CM07, KM06 |
Students' progress in acquiring competences on the course can be monitored through continuous assessment or by a single term-end examination as detailed below.
Assessment of contents taught in Theory classes
The contents taught in Theory classes will have a weight of 80% of the final grade for the subject.
In case of following a continuous assessment, students will have to perform two Interim Tests that the students will have to take individually. These tests will consist of a series of objective questions to show whether the students have assimilated the concepts required to pass the subject, and whether they know how to integrate and interrelate them. These tests will also include questions on the units that students will have prepared on their own in order to evaluate the corresponding learning outcomes.
The First Interim Test will have a weight of 40% of the final mark and will focus on the contents taught up to that moment including two units that students have had to prepare independently.
The Second Interim Test will include the rest of the contents (although some questions can also indirectly refer to aspects of the units evaluated in the First Interim Test). This test will also include two units that students must prepare independently. The weight of this Second Interim Test in the final mark will be 40%.
In case of not passing these tests, or wanting to improve the mark obtained, students will be able to perform a Recovery Exam of the contents corresponding to any of these parts (or both). Each one of these tests will include the contents relatedto the twoprevious Interim Tests and therefore its weight will again be 40%+40% of the final grade.
Students who request a single term-end examination will be able to take a Single term-end Exam that will integrate the whole theoretical content of the subject and will represent 80% of the grade. This test will take place on the same day as the Second Interim Test. These students will also be able to perform a Recovery Exam of this content which will again have a weight of 80% on the final mark and take place concurrently to the Recovery Exam of the students that follow continuous evaluation.
Assessment of contents taught in Problem-based classes
The contents related to the Problem-based classes will account for 20% of the final grade. This portion of the evaluation will assess students' ability to solve experimental problems that are directly related to the theoretical content of the subject.
In each session, several students will be asked to orally present the solutions to the exercises programmed for that session using the presentations they have previously submitted through the Virtual Campus (any modifications or corrections made to the submitted document will not be taken into account for evaluation). If a group fails to submit any of the required exercises, they will receive a 0 for the corresponding session. The teacher will select students to present each exercise to ensure that everyone has the opportunity to present at least one exercise during the course. The teacher will evaluate these presentations not only based on whether the students have understood the problem, correctly interpreted the data, and arrived at the correct answer, but also on their communication skills, clarity, and organization of the presentation. If necessary, the teacher will ask questions to verify that the presenters have genuinely worked on and understood the problem. The grade awarded for each presentation will apply to all group members, regardless of who has given the presentation, and this grade will account for 15% of the final mark for the subject. During these presentations, the participation of other teams will be encouraged, either by discussing the presented results or exploring the possibility of other valid solutions.
Related to this activity, at mid-semester and at the end of the course, all students will be required to submit their responses to a questionnaire regarding the functioning of their team. This questionnaire will be prepared by the teacher and made available to students through the Virtual Campus. In this questionnaire, each team member will evaluate their own participation as well as the participation of their team-mates. The goal is to monitor the development of teamwork and identify students who do not contribute or interfere with the group tasks. Although the results of these questionnaires will not directly contribute to the final grade for the subject, if a student is negatively evaluated by the rest of the team for lack of participation, the final mark for the team will not be applied to that student, or their mark may be lowered accordingly.
On the other hand, the contents of the Problem-based classes will also be evaluated through the individual resolution of a problem similar to the ones worked on during the course. This exercise will be carried out together with the Second Interim Test, and the mark obtained will represent 5% of the final grade for the subject. In the case of following continuous assessment, students will solve this problem together with the Second Interim Test. In case of requesting a single term-end examination, students will solve this problem together with the Single Term-End Exam.
Globally, the maximum mark that can be obtained after completing all these activities will be 10 points (out of 10). To be able to pass the subject, the following conditions must be fulfilled.
- Obtaining a mark equal to or greater than 3,5 points (out of 10) in each Interim Test or in the corresponding interim parts of the Recovery Exam (in case of following continuous assessment).
- Obtaining a mark equal to or greater than 3,5 points (out of 10) in the Single term-end Exam or in the Recovery Exam (in case of following single term-end examination).
- Obtaining an overall mark of ≥5 (out of 10) for all assessments received.
ADDITIONAL ASPECTS
If a student decides to take the Recovery Exam to improve the mark obtained, they will forfeit all previously obtained Theory marks.
To be eligible for the resit exam, students must have been assessed in activities that account for at least 67% of the final grade. Otherwise, they will receive the grade Not Assessable.
For students who do not pass the subject in a given academic year, the marks obtained in the Problem-based classes will be retained for the following year, provided that the competencies associated with these classes have been successfully achieved (i.e., obtaining >5 points out of 10 considering all assessed activities). If the competencies have not been met, students will be required to repeat the evaluation activities to obtain the corresponding grade. This exemption will remain valid for a period of three additional enrollments.
Students who are unable to attend an exam due to extenuating circumstances (such as a health problem, the death of a first- or second-degree relative, an accident, or unavoidable competitions in the case of elite student-athletes) and who provide the official documentation to the degree coordinator (such as an official medical certificate confirming the inability to take the exam, a police statement, or a justification from the relevant sports organization) will be entitled to take the exam on another day. Both the Bachelor’s Degree coordinator and the teacher will make every effort to accommodate these situations.
In this course, the use of artificial intelligence (AI) technologies is permitted exclusively as a support tool, such as for literature search or language revision. The use of AI for content generation in any assessable activity is not allowed. Any work that includes AI-generated content beyond the permitted uses will be considered a breach of academic integrity and may result in a partial or total penalty in the assessment of the activity.
Any irregularity in an assessment activity (academic fraud, plagiarism, or misuse of AI) that may lead to a significant change in the grade will result in a mark of 0 for that activity. In cases of repeated offences, those involved will fail the course. In addition, disciplinary proceedings may be initiated against any student who engages in such irregularities.
Recording images, audio, or any other type of content from teaching sessions is not permitted without the express authorization of the teaching staff. This measure aims to protect image rights, the intellectual property of the content delivered, and the privacy of all participants. Any unauthorized recording may lead to the application of disciplinary measures established in the current university regulations, including those set out in Article 14.4 of the LCU, which may involve the loss of the right to the ordinary assessment sitting of the course and temporary expulsion from the university for up to one month, among other sanctions depending on the severity of the events.
Bibliography
Alberts B, Heald R, Johnson A, Morgan D, Raff M, Roberts K, Walter P, Wilson J. Molecular Biology of the Cell. 7th Edition. Garland Science, 2022.
Last edition of the book in Spanish:
Alberts B, Johnson A, Lewis J, Raff M, Roberts K, Walter P. Biología Molecular de la Célula. 6ª Edición. Ediciones Omega S.A., 2016.
Alberts B, Hopkin K, Johnson A, Morgan D, Roberts K, Walter P, Heald R. Essential Cell Biology. 6th Edition. W. W. Norton & Company. 2023.
Last edition of the book in Spanish:
Alberts B, Bray D, Hopkin K, Johnson A, Lewis J, Raff M, Roberts K, Walter P. Introducción a la Biología Celular. 5ª Edición. Editorial Médica Panamericana, 2021.
Online open access available at the UAB library:
https://bibcercador.uab.cat/discovery/fulldisplay?docid=alma991007029139706709&context=L&vid=34CSUC_UAB:VU1&lang=ca&search_scope=CourseReserves&adaptor=Local%20Search%20Engine&isFrbr=true&tab=CourseReserves&query=course_code,contains,100939&sortby=date_d&facet=frbrgroupid,include,9059604451498349621&offset=0
Cooper GM, Hausman RE. TheCell: A Molecular Approach. 9th Edition. Oxford University Press, 2022.
Last edition of the book in Spanish:
Cooper GM. La Célula. 8ª Edición. Marbán Libros S.L. 2021.
Lodish H, Berk A, Kaiser CA, Krieger M, Bretscher A, Ploegh H, Amon A, Scott MP. Molecular Cell Biology. 9th Edition. WH Freeman and Company, 2021
Last edition of the book in Spanish:
Lodish H, Berk A, Matsudaira P, Kaiser CA, Krieger M, Scott MP, Zipursky SL, Darnell J. Biología Celular y Molecular. 9ª Edición. Editorial Médica Panamericana, 2023.
Online open access available at the UAB library:
https://bibcercador.uab.cat/discovery/fulldisplay?docid=alma991007006029706709&context=L&vid=34CSUC_UAB:VU1&lang=ca&search_scope=CourseReserves&adaptor=Local%20Search%20Engine&tab=CourseReserves&query=course_code,contains,100939
Software
No specific software is used.
Course groups and languages
The information provided is provisional until November 30. After this date, you will be able to consult the language of each group through this link. To access the information, you will need to enter the course CODE
| Type of teaching | Group | Language | Semester | Shift |
|---|---|---|---|---|
| (TE) Theory | 51 | Catalan | first semester | morning-mixed |
| (SEM) Seminars | 511 | Catalan | first semester | morning-mixed |
| (SEM) Seminars | 512 | Catalan | first semester | morning-mixed |