
Organic Chemistry
Code: 101893Credits: 3
| Degree programme | Type | Course |
|---|---|---|
| Biomedical Sciences | OB | 1 |
Contact lecturer
- Name :
- Sira Defaus Fornaguera
- Email :
- sira.defaus@uab.cat
Group languages
You can consult this information at the end of the document.
Prerequisites
The students must have clear the contents of the subject of Chemistry that is taught in first and second of Baccalaureate.
Objectives
Organic Chemistry is the study of the reactivity of carbon. Since living organisms are composed of molecules based on the carbon atom, Organic Chemistry is a fundamental discipline for understanding the life processes of these organisms.
Accordingly, this course aims to provide students with a basic understanding of the structure, chemical equilibrium, conformational analysis, and stereochemistry of organic compounds, and ultimately to relate the structure of these compounds to their chemical reactivity.
Main objectives of the course:
- Introduce the fundamental concepts of structure, chemical bonding, and equilibrium.
- Familiarize students with the nomenclature and structure of organic compounds based on their functional groups.
- Introduce the basic concepts of conformational analysis and the stereochemistry of organic molecules.
- Present the major organic reactions occurring in biological systems.
Learning outcomes
- CM08 (Analyse measurable experimental parameters in tissues in normal or pathological physiological conditions, integrating this data to interpret biological significance.) Analyse measurable experimental parameters in tissues in normal or pathological physiological conditions, integrating this data to interpret biological significance.
- KM10 (Identify functional heterogeneity in tissue and certain experimental methods for its observation.) Identify functional heterogeneity in tissue and certain experimental methods for its observation.
- SM10 (Apply bioinformatics resources when searching for information in databases on molecular and histological processes in the human body.) Apply bioinformatics resources when searching for information in databases on molecular and histological processes in the human body.
Contents
Topic 1. Introduction to Organic Chemistry
Atomic structure. The periodic table. Chemical bonding: ionic and covalent bonds. Lewis structures. Resonance. Molecular geometry. Intermolecular forces.
Topic 2. Acid–Base Equilibria
Brønsted acid–base equilibria. The concepts of pH and pKa: the Henderson–Hasselbalch equation. Physiological buffer systems.
Topic 3. Organic Compounds, Conformational Analysis, and Stereochemistry
Carbon and organic compounds: hydrocarbons and the major functional groups. Isomerism and chirality. Concepts of constitution, conformation, and configuration. Z/E isomerism of alkenes. Stereoisomerism: enantiomers, diastereomers, and meso compounds. Optical activity. Racemic mixtures. Chiral compounds and their importance in living organisms.
Topic 4. Organic Reactions in Biological Systems
Introduction to organic reactions: addition, substitution, and elimination reactions. Oxidation–reduction (redox) reactions. Examples in biological systems.
Learning activities and methodology
| Title | Hours | ECTS | Learning outcomes |
|---|---|---|---|
| Tutorials | 1 | 0.04 | KM10, SM10 |
| Laboratory classes | 8 | 0.32 | KM10, SM10 |
| Study | 30 | 1.2 | CM08 |
| Theory classes | 20 | 0.8 | CM08 |
| Solving problems | 8 | 0.32 | CM08 |
| Problems | 4 | 0.16 | CM08 |
Lectures
Students will attend in-person lectures in which the instructor presents the core scientific and technical concepts of the course. These concepts are intended to provide the foundation for subsequent independent study and deeper understanding. Student participation will be encouraged through interactive teaching methods, including the regular discussion of case studies and problem-solving activities.
Problem-Solving Sessions
Students will reinforce the knowledge acquired during the lectures by solving problem sets. A collection of exercises will be provided for students to work on throughout the course. A selected number of these exercises will be solved during the problem-solving sessions to demonstrate appropriate solution strategies and methodologies. Active student participation will be encouraged throughout these sessions. The instructor will foster critical thinking and logical reasoning skills to enhance students' ability to solve scientific problems.
Laboratory Sessions
The laboratory sessions focus on teaching fundamental laboratory techniques and familiarizing students with the safety procedures required for handling chemical substances. To attend the laboratory sessions, students must provide evidence that they have successfully completed the laboratory safety tests available on the Virtual Campus and confirm that they are familiar with and accept the operating regulations of the Faculty of Biosciences laboratories.
Assessment
Continuous assessment activities
| Title | Weight | Hours | ECTS | Learning outcomes |
|---|---|---|---|---|
| Laboratory | 10% | 0.5 | 0.02 | KM10, SM10 |
| Test of theory and problems (second test) | 50% | 1.5 | 0.06 | CM08, KM10 |
| Evidences | 10% | 0.5 | 0.02 | CM08, SM10 |
| Test of theory and problems (first test) | 30% | 1.5 | 0.06 | CM08, KM10 |
Continuous Assessment (Default Option)
Continuous assessment consists of three components:
- Continuous assessment activities (10%): exercises, quizzes, or other individual or group assignments completed inside or outside the classroom.
- Laboratory (10%): reports on the compulsory laboratory sessions.
- Written midterm examinations (80%): two written exams, weighted 30% for the first midterm and 50% for the second midterm.
To pass the course, students must obtain a minimum grade of 4/10 in each of the three assessment components and an overall weighted average of at least 5/10.
Students who fail the written midterm examination component may take the resit examination on the date established in the academic calendar. To be eligible for the resit examination, students must have sat both midterm examinations. Students who have already passed the course may also take the resit examination to improve their grade, with the understanding that the grade obtained in the resit examination will replace the previous grade. Students wishing to do so must notify the course instructor before the date of the final examination.
From the second enrolment in the course onwards, students who successfully demonstrated the required competencies during the previous academic year will not be required to repeat the laboratory sessions or resubmit the continuous assessment activities.
Students will receive a grade of "Not Assessable" (NA) if they complete less than 50% of the scheduled assessment activities (continuous assessment activities, both midterm examinations, and laboratory sessions).
Single Assessment (Must be requested through the Faculty of Biosciences Academic Office, the Degree Coordinator, and the Course Instructor)
Students opting for the single assessment pathway must complete:
- one comprehensive final examination covering theory and problem-solving (80%);
- one written assignment (10%); and
- the reports for the compulsory laboratory sessions (10%), which must be submitted at the end of each laboratory session together with those of the continuous assessment students.
The single assessment examination will take place on the same date, at the same time, and in the same location as the final continuous assessment examination for the course.
Students will pass the course by obtaining a final grade of at least 5.0 out of 10.
Students following the single assessment pathway may take the resit examination on the date scheduled for the general course resit.
Any irregularity committed during an assessment activity (including academic misconduct, plagiarism, or the unauthorized use of artificial intelligence, unless such use is expressly permitted in the course guide) that may lead to a significant alteration of the assessment outcome will result in a grade of 0 for that assessment. If the course guide establishes that obtaining a minimum grade in that assessment is a compulsory requirement for passing the course, or if multiple irregularities occur in the assessment activities of the same course, the final course grade will be 0. In addition, disciplinary proceedings may be initiated against any student found responsible for such misconduct.
Bibliography
1.- i) Bruice, P.Y. Organic Chemistry, 8th Ed. Ed. Pearson Education, 2017 (ISBN 9781292160344, ISBN1292160349 ).
ii) Bruice, P.Y. Essential Organic Chemistry, 3rd Ed. Ed. Pearson Education, 2016 (ISBN 9781292089034).
2.- Timberlake, K.C. Química: Una Introducción a la Química General, Orgánica y Biológica, 10ª Ed. Ed. Pearson Educación, S.A. 2011 (ISBN 9788483227435).
3.- i) Holum, J.R. Fundamentos de Química General, Orgánica y Bioquímica para Ciencias de la Salud, 1a Ed. Editorial Limusa, México, 1999 (ISBN:968-18-4637-0).
ii) Holum, J.R. Fundamentals of General, Organic and Biological Chemistry, 6th Ed. John Wiley& Sons Publishing, 1997 (ISBN-10 0471175749, ISBN-13 978-0471175742).
iii) Holum, J.R. Elements of General, Organic and Biological Chemistry, 9th Ed. John Wiley & Sons Publishing, 1995 (ISBN 0471059064, ISBN 047111605X).
4.- SolomonsT.W.G. Química Orgánica, 3ª Ed. Ed. Limusa S.A. 2014 (Vol. 1: ISBN 10 9786070506963, Vol 2: 9786070506970).
5.- Carey F.A., Giuliano R.M. Química Orgánica, 9a Ed. Ed. McGraw-Hill, 2014 (ISBN 9786071512109).
6.- Química, (un proyecto para la A.C.S.), Editorial Reverte, 2007 (978-84-291-7001-6).
7- IUPAC Nomenclature of Organic Chemistry:
i) https://iupac.qmul.ac.uk/BlueBook/
ii) https://publicacions.iec.cat/repository/pdf/00000195/00000013.pdf
iii) https://www.upo.es/depa/webdex/quimfis/docencia/quimbiotec/Nomenclatura_organica.pdf
8.- ACD/ChemSketch for Academic and Personal Use. A Free Comprehensive Chemical Drawing Package: http://www.freechemsketch.com
9.- Pulido F. Nomenclatura de Química Orgánica: http://es.slideshare.net/manoa21/nomenclatura-quimicaorganica-29646851?next_slideshow=1
10.- Rosso V. Química Orgánica Nomenclatura: http://es.slideshare.net/verorosso/qumica-orgnica-nomenclatura?qid=09239331-ba5c-4096-9104-dd4cb26fe630&v=qf1&b=&from_search=3
Software
ACD/ChemSketch for Academic and Personal Use. A Free Comprehensive Chemical Drawing Package: http://www.freechemsketch.com
Course groups and languages
The information provided is provisional until November 30. After this date, you will be able to consult the language of each group through this link. To access the information, you will need to enter the course CODE
| Type of teaching | Group | Language | Semester | Shift |
|---|---|---|---|---|
| (TE) Theory | 51 | Catalan | first semester | morning-mixed |
| (SEM) Seminars | 511 | Catalan | first semester | morning-mixed |
| (PLAB40) Pràctiques de laboratori (40 estudiants per grup) | 511 | Catalan | first semester | morning-mixed |
| (PLAB40s) Suport a les pràctiques de laboratori (40 estudiants per grup) | 511 | Catalan | first semester | morning-mixed |
| (SEM) Seminars | 512 | Catalan | first semester | morning-mixed |
| (PLAB40) Pràctiques de laboratori (40 estudiants per grup) | 512 | Catalan | first semester | morning-mixed |
| (PLAB40s) Suport a les pràctiques de laboratori (40 estudiants per grup) | 512 | Catalan | first semester | morning-mixed |