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Biotechnological Plant Projects

Code: 100964
Credits: 6
2026/2027
Degree programme Type Course
Biotechnology OP 4

Contact lecturer

Name :
Francisco Valero Barranco
Email :
francisco.valero@uab.cat

Group languages

You can consult this information at the end of the document.

Prerequisites

It is necessary to choose the option of bioprocess in the bachellor.

Objectives

Learning the methodology to make a design project of an industrial biotechnological plant. Planning and organization of a project. Structure and material included in a project report. To know the use of a design and plant analysis simulator applied to a bioprocess plant.

Learning outcomes

  • CM32 (Plan a process for obtaining biotechnological products.) Plan a process for obtaining biotechnological products.
  • CM33 (Design the different stages necessary to obtain products by biotechnological means.) Design the different stages necessary to obtain products by biotechnological means.
  • CM34 (Design all the stages of obtaining biotechnological products or derivatives taking into account ethical and sustainable development aspects.) Design all the stages of obtaining biotechnological products or derivatives taking into account ethical and sustainable development aspects.
  • KM35 (Explain the bases of design, instrumentation and monitoring of biotechnological processes.) Explain the bases of design, instrumentation and monitoring of biotechnological processes.
  • KM36 (Describe the bases of the design of a biotechnological production process, as well as its environmental implications.) Describe the bases of the design of a biotechnological production process, as well as its environmental implications.
  • SM32 (Apply safety standards both in the laboratory and in the design of biotechnological plants.) Apply safety standards both in the laboratory and in the design of biotechnological plants.

Contents


  1. Project Management


    1. Project definition. Project Life cycle. Engineering, construction, Operation.

    2. Planning fundamentals. Objectives, product definition, market, reports, economical analysis.

    3. Project planning, Planning tools.

    4. Design variable analysis.

    5. Planning batch operation

    6. Flux diagrams. Simulation programs

    7. Process economics

    8. GMP, PAT i QbD.

    9. Project plant design.


      1. Basic information, specifications, other information.

      2. Graphic information. Process, Engineering (P&I), Layout, services.

      3. Plant services: water, air, heating and cooling, CIP, SIP.

      4. Sizing of equipments: Equipment list, Control schemes.

      5. Layout.

      6. Safety, Environmental, Operational and procedures. 


 


 

Learning activities and methodology

Title Hours ECTS Learning outcomes
Preproject of bioprocess plants 95 3.8
Theoretical classes 27 1.08
Collaborative work in seminars 12 0.48
Computer center 13 0.52

In addition to the theoretical classes, sessions will be held in the computer classroom to learn and master the bioprocess simulator SuperproDesigner and seminars sessions where the development of the advanced project of an industrial plant of some bioprocess. All these classes and sessions are specified in the subject schedule.

 

Annotation: within the schedule set by the centre or degree programme, 15 minutes of one class will be reserved for students to evaluate their lecturers and their courses or modules through questionnaires.

Assessment

Continuous assessment activities

Title Weight Hours ECTS Learning outcomes
Memory of the project of the design of a plant of bioprocesses 40% 0 0 CM32, CM33, CM34, KM35, KM36, SM32
Presentation of a design guide of an equipment of a Biotechnological plant 5% 0.5 0.02 CM33
Final Examn 25% 2 0.08 CM32, CM33, CM34, KM35, KM36, SM32
Presentation of the project of the design of a plant of bioprocesses 30% 0.5 0.02 CM32, KM36

Individual final written examination: 25% of note.

Continued evaluation of seminar sessions and progress of bioprocess plant: 40% of note.

Advocacy in public session of the bioprocess plant project: 30% of the note.

Presentation of a guide to design a team of a biotechnology plant: 5% of the note.

For each assessment activity, a place, date and time of review will be indicated where the student can review the activity with the faculty. In this context, complaints can be made about the activity note, which will be evaluated by the teacher responsible for the subject. If the student does not show up for this review, this activity will not be reviewed later.

Honorary tuition (MH). The award of an honorary degree is decided by the faculty responsible for the subject. The UAB regulations state that MH may only be granted to students who have obtained a final grade equal to or greater than 9.00. Up to 5% of all enrolled students can be awarded MH.

It allows the use of Artificial Intelligence (AI) technologies exclusively in support tasks, such as bibliographic or information fencing, text correction or translations. The student will have to clearly identify which parts have been generated by this technology, specify the aspects and include a critical reflection on how these have influenced the process and the final result of the activity. The non-transparency of the use of AI in this evaluable activity is considered a lack of academic honesty and may entail a partial or total penalty in the activity grade, or major sanctions in cases of seriousness.

Any irregularity committed during an assessment (academic fraud, plagiarism, or misuse of AI, unless expressly authorized in the course syllabus) that could lead to a significant change in the grade will result in a grade of 0 for that assessment. If the course syllabus stipulates that passing the course requires committing several irregularities in the assessments of the same course, the final grade for that course will be 0. Furthermore, disciplinary proceedings may be initiated against any student who commits any of these irregularities

This subject/module does not include a single assessment system.


Bibliography

   - E. Heinzle, A. Biwer, C. Cooney “Development of Sustainable Bioprocesses”. Wiley (2006).

                         - R. Turton et al.: “Analysis, Synthesis, and Design of Chemical Processes” 3rd ed. Prentice Hall (2009)

                         -  Sinnott R.K. “ Coulson&Richardson Chemical Engineering. Volume 6: Design”. Elsevier Butterworth-Heinemann (2005).

                  - H.C. Vogel, C.L. Todaro. “Fermentation and Biochemical Engineering Handbook” Noyes (1997).

                         - B. Atkinson, F. Mavituna “Biochemical Engineering and Biotechnology                   

                         - Handbook” Macmillan (1991).

                         - Rudd D.F. Watson Ch.C. “Estrategia en Ingeniería de Procesos” Alhambra (1976).

Software

Programa Superpro Designer. Plant design version 8.5

Excel. Economic analysis.

Course groups and languages

The information provided is provisional until November 30. After this date, you will be able to consult the language of each group through this link. To access the information, you will need to enter the course CODE

Type of teaching Group Language Semester Shift
(TE) Theory 44 Catalan first semester morning-mixed
(PLAB) Practical laboratories 441 Catalan first semester afternoon
(SEM) Seminars 441 Catalan first semester morning-mixed