
Analysis and Synthesis of Bioprocesses
Code: 100962Credits: 6
| Degree programme | Type | Course |
|---|---|---|
| Biotechnology | OB | 3 |
Contact lecturer
- Name :
- Pau Ferrer Alegre
- Email :
- pau.ferrer@uab.cat
Teaching staff
- Xavier Garcia Ortega
- Arnau Gasset Franch
Group languages
You can consult this information at the end of the document.
Prerequisites
The syllabus does not determine any specific prerequisite for this subject. However, due to its integrating nature of the different knowledge acquired throughout previous courses, the recommendation is to have passed the maximum number of subjects possible before taking it. In any case, they are essential to be able to properly follow the basic principles of bioprocess engineering, bioreactors and separation and purification processes.
Objectives
Acquire comprehension and practice in the analysis of biotechnological processes in terms of engineering, economics, compliance with regulations, quality, intellectual property, etc.
Introduce to the student the most important tools used in the analysis and to be able to use these tools in the evaluation and comparison of different solutions (proposals) of design of a determined process.
Overall, it is a subject where we intend to integrate / synthesize knowledge acquired in other subjects of the degree for the design (synthesis and analysis) of bioprocesses.
Learning outcomes
- CM20 (Propose the appropriate design of a bioreactor according to its application.) Propose the appropriate design of a bioreactor according to its application.
- CM21 (Design an industrial process taking into account ethical and sustainable development aspects.) Design an industrial process taking into account ethical and sustainable development aspects.
- KM21 (Illustrate an industrial process for obtaining products by biotechnological means from basic discovery to market introduction.) Illustrate an industrial process for obtaining products by biotechnological means from basic discovery to market introduction.
- SM18 (Apply the kinetic and enzymatic methods necessary for the operation of a bioreactor.) Apply the kinetic and enzymatic methods necessary for the operation of a bioreactor.
- SM19 (Use a bioreactor appropriately.) Use a bioreactor appropriately.
Contents
1. Analysis of bioprocesses
1.1. Characteristics of the biotechnological industries.
1.2. Structure of bioprocesses. The stages of the development and design of a process.
1.3. Analysis of bioprocesses: Economic, environmental and social sustainability assessment.
2. Synthesis of bioprocesses: Selection, arrangement and integration of steps of bioprocesses
2.1. Synthesis of the biocatalyst.
2.2. Synthesis of upstream stages and of the cultivation/bioreaction system and strategy.
2.3. Synthesis of the recovery and purification stages of the product.
2.4. Bioprocess integration and intensification. Biorefineries
2.5. The quality of the process and product.
3. Design of bioprocesses:
3.1. Biotechnology applied to human and animal health.
3.2. Industrial biotechnology and agro-food.
3.3. Environmental biotechnology.
Learning activities and methodology
| Title | Hours | ECTS | Learning outcomes |
|---|---|---|---|
| Seminars | 15 | 0.6 | CM21, KM21 |
| Compulsory group work | 50 | 2 | CM21, KM21 |
| Theoretical classes | 30 | 1.2 | CM20, CM21, KM21, SM18, SM19 |
| self study | 47 | 1.88 | CM20, CM21, KM21, SM18, SM19 |
Use of AI: For this subject, the use of Artificial Intelligence (AI) technologies is allowed exclusively in tasks to support the preparation of group work on a biotechnological process case in its initial phase, that is, in the bibliographic or information search, the correction of texts or the translations of texts obtained from other sources. The student will have to clearly identify which parts have been generated with this technology, specify the tools used and include a critical assessment on how they have influenced the process and the final result of the activity. The non-transparency of the use of AI in this evaluable activity will be considered a lack of academic honesty and may lead to a partial or total penalty in the grade of the activity, or greater sanctions in cases of severity.
Assessment
Continuous assessment activities
| Title | Weight | Hours | ECTS | Learning outcomes |
|---|---|---|---|---|
| Recovery exam | 75% | 2 | 0.08 | CM20, CM21, KM21, SM18, SM19 |
| Partial exams | 75% | 6 | 0.24 | CM20, CM21, KM21, SM18, SM19 |
| Compulsory group work | 25% | 0 | 0 | CM21, KM21 |
During the course, three partial exams will be carried out, previously announced, which will represent 75% of the final mark as a whole. To do the average with the rest of the marks, a minimum mark of 4 (out of 10) is needed in each partial exam.
The compulsory group work, selected from the 4 case studies of the syllabus presented in the Seminars sessions, will represent 25% of the final grade.
To participate in the recovery exam, the students must have previously been evaluated in a set of activities whose weight equals to a minimum of two thirds of the total grade of the subject or module. Therefore, students will obtain the \"Non-Valuable\" qualification when the evaluation activities carried out have a weighting of less than 67% in the final grade
Students who do not pass the partial examinations may perform a recovery exam of the whole theoretical part, which will have a weight of 75% (which will be added to the the compulsory group work assessment with a 25% weight that is not recoverable). Those students who have passed two of the three partial examinations with a mark of 6 or higher, but in one of the partial examinations did not reach the minimum mark to do the average, can be evaluated of this part only.
Single-call evaluation
The single-call evaluation consists of a single synthesis exam that covers the whole theory program of the subject (that is, it replaces the three partial exams). The synthesis exam will have the same type of questions as the partial exams. This exam will have a weight of 75 % of the overall subject.
Students that choose the single-call evaluation modality must participate in the group work case study. The evaluation and weight on the overal grade of the group work assignement will be the same as for the continuous evaluation modality (25%).
The syntesis exam will bescheduled on the same day that the last partial exam of the continuous evaluation, and the same second-chance examination procedure will apply.
To pass the subject, a minimum grade of 4 (over 10) must be achieved in the synthesis exam.
The consumation of any irregularity in an evaluation act (academic fraud, plagiarism or improper use of AI, unless such use is expressly authorized in the teaching guide), which may lead to a significant variation in the grade, means that this act will be graded with a 0. In the event that the teaching guide provides that in order to pass the subject it is an essential requirement to have obtained a minimum grade in this evaluation act or that there are several irregularities in the evaluation acts of the same subject, the final grade of this subject is 0. Besides, a disciplinary process may be initiated against the student who incurs in any of these irregularities.
Bibliography
- Heinzle E., Biwer A., Cooney C. 2006. Development of Sustainable Bioprocesses:Modelling and Assessment. John Wiley & Sons, Ltd. (ref. biblioteca UAB: 66.09, CDROM:RED/674).
- Atkinson B., Mavituna F. 1991. Biochemical Engineering and Biotechnology Handbook. (ref. biblioteca UAB: 66.09Atk)
- Flickinger M.C., Drew S.W. 1999. Encyclopedia of Bioprocess Technology:Fermentation, Biocatalysis and Bioseparation. John Wiley and Sons, Inc. (ref. bibliotecaUAB: 66.09)
- Turton R., Bailie R.C., Whiting W.B., Shaeiwitz J.A. 2003. Analysis, synthesis, and design of chemical processes. 2nd edition. Prentice Hall PTR. (ref. biblioteca UAB: 66.02Ana)
- Biotechnology: a multi-volume comprehensive treatise (edited by H.J. Rehm and G. Reed) 2nd completely revised edition. Weinheim, VCH, 1993-2001 (ref. biblioteca UAB: 5(03) 79 Bio).
- Kirk-Othmer Encyclopedia of Chemical Technology (recurs electrònic) (Accés restringit als usuaris de la UAB: http://onlinelibrary.wiley.com/book/10.1002/0471238961)
Software
In order to elaborate and present the assay on the case study, alumni will have to use a standard ofimatics software
Course groups and languages
The information provided is provisional until November 30. After this date, you will be able to consult the language of each group through this link. To access the information, you will need to enter the course CODE
| Type of teaching | Group | Language | Semester | Shift |
|---|---|---|---|---|
| (TE) Theory | 43 | Catalan | second semester | morning-mixed |
| (SEM) Seminars | 431 | Catalan | second semester | morning-mixed |
| (SEM) Seminars | 432 | Catalan | second semester | morning-mixed |
| (SEM) Seminars | 433 | Catalan | second semester | morning-mixed |
| (SEM) Seminars | 434 | Catalan | second semester | morning-mixed |