Theoretical classes: 25 sessions. Systematized exposition of the syllabus of the subject, giving relevance to the most important concepts. The students acquire the basic scientific knowledge of the subject in theory classes, which will complement the personal study of the topics discussed and with problem-based learning methodology. Students can find a summary of the material used in class in the Virtual Campus and / or Moodle before or after the lecture.

Classroom practices: 11 sessions distributed in 7 Seminar sessions that consist of the presentation of relevant topics of the subject and clinical cases (ABP sessions) in small groups, allowing students to review those most important or most basic topics necessary for understanding the subject, and 4 Genetic Problems sessions, in which cases and genetics problems presented by the teaching staff are presented and resolved.

Laboratory practices: 3 sessions. Exposure and application of the different techniques used in basic and molecular cytogenetics, interpretation of structural and polymorphic variants, and their clinical applicability.

IMPORTANT NOTE: Prior to the completion of laboratory practices, students must have completed the test that certifies the knowledge of the contents of the risk prevention manual and upload it to the Virtual Campus and / or Moodle. They are essential requirements to perform practices 1 and 2 take a lab coat and show the teacher a signed copy of the risk prevention test.

For this course, the use of Artificial Intelligence (AI) technologies is permitted exclusively for support tasks, such as bibliographic or information searches, text proofreading, translations, and the resolution of problems and clinical cases. Students must clearly identify which parts have been generated using this technology, specify the tools used, and include a critical reflection on how these tools have influenced both the process and the final outcome of the assignment. Failure to disclose the use of AI in this assessed activity will be considered a breach of academic integrity and may result in a partial or total reduction of the assignment grade, or more severe disciplinary sanctions in cases of greater seriousness.

Annotation: within the schedule set by the centre or degree programme, 15 minutes of one class will be reserved for students to evaluate their lecturers and their courses or modules through questionnaires.

Evaluation

A. The competences acquired in theory classes, classroom practices (Seminars and Genetic Problems) of this subject will be evaluated as follows:

1. Continuous evaluation: it will be divided into two partial exams:

First partial:

• Multiple-response objective test (single- or multiple-choice, with marking criteria to be specified in the corresponding exam announcement) of the knowledge acquired in theory classes (topics 1-13) and PAUL Seminars 1-3. This test must be passed with a grade of 4,8 or higher to be used for the average. This test corresponds to 35% of the final grade of the subject.

Second partial:

• Multiple-response objective test (single- or multiple-choice, with marking criteria to be specified in the corresponding exam announcement) of the knowledge acquired in theory classes (topics 14-25) and PAUL Seminars 4-7. This test must be passed with a grade of 4,8 or higher to be used for the average. This test corresponds to 35% of the final grade of the subject.

• Objective written test or multiple-response objective test (single- or multiple-choice, with marking criteria to be specified in the corresponding exam announcement) of questions related to classroom practices (Genetic Problems). This test corresponds to 10% of the final grade of the subject.

2. Recovery exam: Students who have been previously evaluated for at least 2/3 of the total qualification and therefore having presented the 2 partials corresponding to the continuous assessment, may be attending to the final exam under the following situations:

• Students who have obtained a grade below 4,8 of the theory part and PAUL Seminars in any of the two partials.

• Students who have obtained a grade equal to or greater than 4,8 of the theory part and PAUL Seminars in one or both partial tests but the average for this part of the evaluation does not reach 5.

• Students who want to upload a grade of one or both of the partials, or of the PAUL Genetic Problems. The grade obtained in the final exam will be maintained.

This exam contains:

• Multiple-response objective test (single- or multiple-choice, with marking criteria to be specified in the corresponding exam announcement) corresponding to each partial. The student will choose to perform one or both tests depending on their situation. This test must be passed with a grade of 4,8 or higher to be used for the average. Each test will correspond to 35% of the final grade of the subject.

• Objective written test or multiple-response objective test (single- or multiple-choice, with marking criteria to be specified in the corresponding exam announcement) of questions related to PAUL Genetic Problems. This test corresponds to 10% of the final grade of the subject.

B. The competences acquired in the laboratory practices will be evaluated by continuous evaluation through a written test at the end of each practice. The average of the three tests corresponding to the three laboratory practices will be used to obtain the final grade. It is not necessary that the average of the three tests equal or exceed 5 to pass the course. Failure to show up to practice and, therefore, not perform the corresponding written test, represents a 0 in that laboratory practice.

The repeating students will only have to return to those lab sessions in which they have not reached a grade equal to or higher than 6 in the test of the corresponding practice, provided that this mark has been obtained in the last two years.

C. The final grade will be obtained as follows:

Theory and PAUL Seminar tests: 70% of the final grade

Tests of PAUL Genetic Problems: 10% of the final grade

Tests of laboratory practices: 20% of the final grade

-Partial and final exams must reach marks of 4,8 or higher to be used for the average, as long as this average reaches 5.

-To pass the subject it will be necessary to obtain a global grade equal to or greater than 5 out of 10.

-The \"Non-evaluable\" will reflect the non-attendance to the final exam of recovery for students who have not passed the subject previously in the partial exams or who have to evaluate the whole subject through the final exam of recovery.

D. In the case that the student does not exceed the assessment requirements of the subject and its average grade of is greater than 5, the final grade cannot be higher than 4.8.

Review of the exams

After each one of the exams of the subject, the review of the exam will be convened during which the students will be able to consult their exam and, if necessary, make a written and reasoned claim.

Single evaluation

Students undertaking this course may choose the single assessment system, according to the Faculty's regulations. The single assessment will be based on the same content course, the acquisition of the same skills, and will achieve the same level of demand as the continuous assessment.

The single assessment test will take place the same date fixed in the calendar for the last continuous assessment test and the same recovery system will be applied as for the continuous assessment. The single assessment will consist of one testr with the two parts corresponding to the two blocks of partials (including the classroom practice exam) and the tests corresponding to the three laboratory practices. The weight of each assessment activity will be the same as in the case of continuous assessment. To pass the subject through the single assessment system, each student must meet all the requirements indicated in the continuous assessment system.