Guide in PDF format
Logo

Organ and Tissue Transplants

Code: 103603
Credits: 3
2026/2027
Degree programme Type Course
Medicine OP 5

Contact lecturer

Name :
José Montiel Serrano
Email :
jose.montiel@uab.cat

Group languages

You can consult this information at the end of the document.

Prerequisites

It is absolutely necessary to have achieved sufficient knowledge in:
 
General and specific anatomy of the different organs and systems.
General and specific physiology of different organs and systems.
Cell biology, biochemistry and molecular biology.
and it is advisable to have begun in the knowledge of the study of the different medical and surgical pathologies and in the clinical practice.
 
The student will acquire the commitment to preserve the confidentiality and professional secret of the data to which he can access because of the learning in the welfare services. Also to maintain an attitude of professional ethics in all its actions.

Objectives

The subject, under the mention of Clinical Surgery, is scheduled for the fifth year of the Degree of Medicine, once the basic knowledge about the structure and function of the human body has been obtained and of introducing itself to the knowledge of the " Study of the different medical and surgical pathologies and in clinical practice
 
Its general objective is to introduce the student to the world of the transplant of organs and tissues. Although many of the concepts have been able to be described in other subjects, the social, ethical, legal and medical problems make it convenient to frame from a global point of view.
 
The specific training objectives are that the student be able to know the laws that regulate the transplant in our country and our environment, detect the different sources of organs, describe the basic principles of obtaining and maintaining the organs, defining the Concepts of biological identity and rejection, describe the modulation of the immune response, list the indications and the main technical characteristics and the complications of each of the organic transplants, the conditions for the establishment of a body of organs, objectively discuss the problems ethics and the clinical application of transplants, know the main lines of basic and clinical research and the problems that are pending in the field of the transplant.

Learning outcomes

  1. Identify the ethical bases for decision-making in the field of surgery.
  2. Transmit the information on the surgical procedure to be performed and draw up a document of informed consent.
  3. Manage the information available and set levels of discussion in multidisciplinary groups.
  4. Back decision-making with the best scientific evidence.
  5. Anticipate and compare information for good decision-making.
  6. Participate in the whole process of patient-care, from diagnosis to aftercare.
  7. Justify decisions taken based on the information obtained.
  8. Make a critical analysis of the objectives to be achieved with surgery, contrasting this with the adverse effects that may be involved.
  9. Encourage the search for answers to the questions that arise during surgery.
  10. Critique original or review scientific papers.
  11. Evaluate the appropriate scientific methodology for a biomedical paper.
  12. Use the specific bibliographic sources that will help to develop further one's knowledge.
  13. Build diagnostic and therapeutic algorithms based on the best scientific evidence, taking into account the facilities available.
  14. Establish a working hypothesis and its objectives.
  15. Choose the best possible research design to respond to the hypothesis put forward.
  16. Define the statistical methodological bases.
  17. Formulate and discuss the results obtained.
  18. Present results orally or in writing.
  19. Identify funding sources and set up a budget.
  20. Integrate all pre-operative information for decision-making.
  21. Calculate the surgical risk indices, both general and by apparatus, and adjust the indications accordingly.
  22. Provide the bases for preparing clinical guides and constructing diagnostic and therapeutic algorithms.
  23. Apply basic surgical manoeuvres in practice with simulated models.
  24. Gather information and select the most important facts about the patient, both in normal visits and emergencies.
  25. Describe biomedical bibliographic databases and ways to filter the information provided.
  26. Choose content in accordance with the rules of evidence-based medicine.
  27. Identify the legal bases for creating, maintaining and using databases that contain medical information.
  28. Maintain and sharpen one's professional competence, in particular by independently learning new material and techniques and by focusing on quality.
  29. Convey knowledge and techniques to professionals working in other fields.
  30. Be able to work in an international context.
  31. Use information and communication technologies in professional practice.

Contents

1. History, concepts and type of transplants.

2. Immunosuppression. Concepts applied to transplantation. Drugs and patterns of immunosuppression.

3. Obtención de órganos y tejidos. The organ donor. Brain death Selection of organs. Ethical concepts.

4. Coordination of transplants.

5. Surgical techniques for the removal and preservation of organs.

6. Renal transplantation. Indications, preparation, immunosuppression guidelines and results.

7. Renal transplantation. Surgical technique and complications.

8. Liver transplantation. Indications, preparation, immunosuppression guidelines and results.

9. Liver transplantation. Surgical technique and complications.

10. Pancreatic transplant. Indications, preparation, immunosuppression guidelines and results. Surgical technique and complications.

11. Pulmonary transplantation. Indications, preparation, immunosuppression guidelines and results.

12. Pulmonary transplantation. Surgical technique and complications.

13. Cardiac transplantation. Indications, preparation, immunosuppression guidelines and results. Surgical technique and complications.

14. Intestinal transplantation. Indications, preparation, immunosuppression guidelines and results. Surgical technique and complications.

15. Tissue transplantation. The tissue banks.

Learning activities and methodology

Title Hours ECTS Learning outcomes
WORK LABOR / PERSONAL STUDY / READING OF ARTICLES / INTEREST REPORTS 43 1.72
THEORY (TE) 15 0.6
ASISTENCIAL CLINICAL PRACTICES (PCAh) 15 0.6
This Guide describes the framework, contents, methodology and general rules of the subject, in accordance with the current curriculum. The final organization of the subject with respect to the number and size of groups, distribution in the calendar and dates of examinations, specific criteria for evaluation and review of exams, will be specified in each of the hospital teaching units (UDH), which will be explained through their web pages and the first day of class of each subject, through the professors responsible for the subject in the UDH.
 
For the present year, the professors designated by the departments as responsible for the subject at the Faculty level and the UDH are:
 
Responsible department (s):
 
Head of Faculty: Joan Morote Robles - jmorote@vhebron.net
 
Responsible UDHSP
Josep Maria Padró Fernández jpadro@santpau.cat
 
Responsible UDHVH
Joan Morote Robles jmorote@vhebron.net
 
 Responsible UDGTiP Responsables UDHPT
NO OFFER IS NOT OFFERED
 
 
General teaching methodology:
 
DIRECTED TEACHING TYPES: (~ 20% Classroom theory theory; clinical laboratory practices, clinical case seminars and clinical assistance practices)
 
Theory (TE typology). Group size: enrollment group. Scheduled sessions 15 (1 h per session).
 
Asistencial clinical practices (PCAh typology) (15 hours)
 
Period of unregulated curricular practices corresponding to studies in the field of health, during which the students experience in a real context and acquire specific skills under the direct supervision of the UAB professors or of external professionals involved.
 
AUTONOMOUS WORK (57% total 43 hours)
 
Comprehensive reading of texts and articles, study and realization of schemes, summary and conceptual assimilation of the contents. Preparation of presentations and deliveries.
 
EVALUATION (3% total 2 hours)

In the current exceptional circumstances, at the discretion of the teachers and also depending on the resources available and the public health situation, some of the theoretical classes, practicals and seminars organized by the Teaching Units may be taught either in person or virtually.

Annotation: within the schedule set by the centre or degree programme, 15 minutes of one class will be reserved for students to evaluate their lecturers and their courses or modules through questionnaires.

Assessment

Continuous assessment activities

Title Weight Hours ECTS Learning outcomes
Syllabus_Practicum 30% 1 0.04 1, 10, 11, 14, 15, 19, 21, 23, 29
Continuous evaluation: Assistance and active participation in classes and seminars 30% 0 0 1, 2, 4, 6, 8, 9, 14, 15, 19, 20, 21, 24, 25, 28
Written evaluation through multiple choice objective tests / restricted questions essay tests 40% 1 0.04 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 26, 27, 29, 30, 31

It will be necessary for the student to attend 80% of the supervised and supervised activities and present a syllabus of their activities. A continuous assessment will be made and finally there will be an objective multiple choice test.

This subject does not provide the single assessment system.

Bibliography

Bibliografia específica

  1. López Navidad A, Kulisevsky J, Caballero F. El donante de órganos y tejidos: evaluación y manejo. Spring-Verlag Ibérica. Barcelona, 1997.
  2. Manyalic M, Cabrer C. Transplant Coordination Manual. TPM-Les Heures-Universitat de Barcelona-Fundació Bosch Gimpera. Barcelona, 2001.
  3. Küss R, Bourget P.Una historia ilustrada del trasplante de órganos. Rueil-Malmaison: Laboratoires Sandoz, 1992..
  4. Neuberger J, Adams D. Immunology of liver transplantation. Edward Arnold, 1993.
  5. Flye MW. Principles of organ transplantation. WB Saunders. Philadelphia, 1989.
  6. Flye MW. Atlas of organ transplantation. WB Saunders. Philadelphia, 1995.
  7. Henriksen AJ, Simmons RL, Finch ME, Ascher NL. Manual of vascular access, organ donation and transplantation. Springer, 1984.
  8. Kremer B, Broelsch CE, Henne-Bruns D. Atlas of Liver, Pancreas and Kidney Transplantation. Georg Thieme Verlag. Stuttgart, 1994.
  9. Caralps A, Gil-Vernet JM, Vives J. Cirugía del trasplante renal. Ed Toray SA. Barcelona, 1983.

Bibliografia de consulta

  1. Arias M, Campistol, JM, Matesanz R, Morales JM, Ortega F. Trasplante renal. Editorial Médica Panamericana. Madrid, 2007.
  2. Asfar S, Zhong R, Grant D. Small bowel transplantation. Surg Clin North Am October 1994; 74 (5): 1197-1210.
  3. Asher NL, Hansen JA, Strom T. Year Book of Transplantation 1992. San Luis: Mosby Year Book, 1992.
  4. Berenguer J, Parrilla P. Trasplante Hepático. Elba S.A. Madrid, 1999.
  5. Bussutil RW, Klintmaln G. Transplantation of the liver.: WB Saunders. Philadelphia, 1995.
  6. Calne RY, ed. Liver Transplantation. Grune & Straton. New York, 1983.
  7. Carpentier A, Farge D, eds. Transplantation D'organes. Flammarion. Paris, 1992.
  8. Cerilli GJ. Organ transplantation and replacement.: Lippincot. Philadelphia, 1988.
  9. Cuervas Mons V, del Castillo Olivares JL. Introducción al trasplante de órganos y tejidos.: ELBA Madrid, 1994.
  10. Cuervas Mons V. Trasplante hepático. Sandoz Pharma. Barcelona, 1993.
  11. Dousset B, Houssin D. Greffes du foie chez l'enfant. Rev Pract Jun 1994; 44 (11): 1500-1507.
  12. Lake JR, ed. Advances in Liver Transplantation. Gastrl Clin N Am June 1993; 22: 213-473.
  13. Makowka L. The handbook of transplantation management. Austin: RG Landes, 1991.
  14. Moreno González E, Gómez Sanz R. Presente y futuro del trasplante de órganos abdominales. Jarpyo ed., 1997.
  15. Roit I, Brostoff J, Male D. Immunology. 3ª ed. Gower Medical Publishing. New York, 1993.
  16. Salvatierra O, Lum CT, eds. History of the American Society of Transplant Surgeons. Minneapolis: Stanton Publication Services for the American Society of Transplant Surgeons, 1994.
  17. Starzl TE. El hombre puzzle. JR Prous Edotores, Barcelona, 1994.
  18. Starlz TE, Shapiro R, Simmons RI. Atlas of organ transplantation. Gower Medical Publishing. New York, 1992.
  19. Starlz TE, Demetris AJ. Liver transplantation: A 31-year perspective. Curr Probl Surg. February 1990; pt I 51-116.
  20. Starlz TE, Demetris AJ. Liver transplantation: A 31-year perspective. Curr Probl Surg. March 1990; pt II: 119-178.
  21. Starlz TE, Demetris AJ. Liver transplantation: A 31-year perspective. Curr Probl Surg. April 1990; pt III: 183-240.
  22. Talbot-Wright R, Carretero P. Manual del trasplante renal. Editorial Médica Panamericana. Madrid, 1998.
  23.  Willians JW. Hepatic Transplantation. WB Saunders. Philadelphia, 1990.


Recursos d’Internet

Organització Catalana de Trasplantament: http://www10.gencat.cat/catsalut/ocatt/es/htm/index.htm

Organización Española de Trasplante: http://www.ont.es/Paginas/default.aspx

European Society of Organ Transplantation: http://www.esot.org/

American Society of Transplant Surgeons: http://www.asts.org/

European Liver Transplant Registry: http://www.eltr.org/

Scientific Registry of Transplant Recipients: http://www.ustransplant.org/

United Network for organ sharing: http://www.unos.org/

International Society for Heart & Lung Transplantation: http://www.ishlt.org/

International PancreasTransplant Registry : http://www.iptr.umn.edu/

Intestinal Transplant Association: http://www.intestinaltransplant.org/

Software

No specific software required

 

Course groups and languages

The information provided is provisional until November 30. After this date, you will be able to consult the language of each group through this link. To access the information, you will need to enter the course CODE