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Pharmacology

Code: 102665
Credits: 9
2026/2027
Degree programme Type Course
Veterinary Medicine OB 3

Contact lecturer

Name :
Carles Cristòfol Adell
Email :
carles.cristofol@uab.cat

Teaching staff

Fernando de Mora Pérez
Carles Cristòfol Adell
Alheli Rodriguez Cortes

Teaching staff (external to UAB)

Rubén Foj Ibars
Margarita Arboix Arzo
Professor substitut 2
María Llorian Salvador
Clara Martori Montsant
Professor substitut 1

Group languages

You can consult this information at the end of the document.

Prerequisites

 

PHYSIOLOGY (general concepts on organs and systems functioning)

BIOCHEMISTRY (molecular mechanisms of the basic functions of the organism)

Objectives

Contextualisation. Third year studies degree (first semester and first half of second semester).

General objectives: Provide the student with the fundamental concepts in the field of pharmacology. Studying drugs, their mechanism of action and their effects, as the basics of therapeutic pharmacology

Educational Objectives: Acquisition of the basic principles of pharmacokinetics (drug delivery, absorption, distribution, metabolism and excretion), and pharmacodynamics (mechanism of action), interactions and adverse drug reactions, underlying the rational and appropriate use of drugs in the different fields of applied pharmacology.

 

Learning outcomes

  1. Communicate information obtained during professional exercise in a fluid manner, orally and in writing, with other colleagues, authorities and society in general.
  2. Apply scientific method to professional practice, including medicine
  3. Demonstrate knowledge of English to communicate both orally and in writing in academic and professional contexts.
  4. Explain and analyse the phases of the transport of drugs through the organism, i.e. drug kinetics.
  5. Explain and analyse the molecular and cellular action mechanism of drugs and its effect.
  6. Identify adverse effects and interactions of drugs and analyse the benefit-risk quotient in the administration of drugs.
  7. Identify and interpret the phases of drug development and know the bodies involved in their development and authorisation.
  8. Apply the methodology for pharmacokinetic and pharmacodynamic analysis of molecules and defend the results.
  9. Explain and defend the pharmacology of the agents that act in different systems, organs and apparatus.
  10. Explain the drugs that act in the central and peripheral nervous system.
  11. Identify aspects of pharmaceutical technology that are relevant to the stability of medicines.

Contents

THEORETICAL / PRACTICAL PROGRAM / EXAMS *


THEORY


Introduction to Pharmacology


I. Pharmacokinetics

ADME processes. Drug administration and absorption. Distribution of drugs in the body. Biotransformation of drugs. Drug excretion. Pharmacokinetics.


II. Pharmacodynamics

General principles of drug action. Pharmacological targets: receptors. Type of receptors. Channel-coupled receptors, G protein-coupled receptors, which control gene transcription. Regulation of the receptors: up- and down-regulation. Other pharmacological targets. Antibodies as selective drugs.


III. Factors that limit drug efficacy

Drug interactions. Adverse drug reactions.


IV. Drugs acting on the Autonomous/peripheral Nervous System

General aspects of the pharmacology of the peripheral nervous system. Pharmacology of the cholinergic transmission. Pharmacology of noradrenergic transmission. Pharmacology of the motor plaque.


V. Systemic pharmacology

Drugs that act on the cardiovascular system. Drugs that act on the respiratory system. Drugs that act on hemostasis. Pharmacology of the digestive system. Drugs with diuretic action. Pharmacological regulation of the endocrine system.


VI. Pharmacology of the Central Nervous System


Central nervous system: general considerations. Analgesics. Sedative and tranquilizer agents. Antidepressants, Antiepileptic and anticonvulsant drugs. Anesthetic drugs.


VII. Anti-inflammatory, anti-allergic and immunomodulatory drugs

Steroids. Non-steroidal anti-inflammatory drugs (NSAIDs). Antihistamine drugs Immunomodulatory drugs. Others agents acting on the immune system.

VIII. Anti-infective drugs

General principles of the pharmacology of antimicrobials. Betalactamics: Penicillins and Cephalosporins. . Aminoglycosides and Polypeptides. Quinolones Sulfamides. Tetracyclines and Phenolic. Macrolides and Lincosamines. Antimicotic and antivirals. Antiparasitic agents: Anthelmintics, Ectoparasitic and Antiprotozoa.


IX. Anticancer drugs

Cytotoxic agents and other anticancer.


X. Others

Sources for obtaining new drugs



- PRACTICAL SESSIONS

Analitical method (experimental lab). Absorption of drugs (experimental lab). Protein binding (experimental lab). Drug excretion (experimental lab). Pharmaceutical Forms and Formulation (experimental lab). Pharmacokinetic cases (classroom). Journal club (classroom). Drug Discovery (seminar). Case study 1 (classroom). Neuromuscular Junction (computer science). Case 2 (classroom). Organ bath: cholinergic drugs (experimental lab). Case 3 (classroom). RatCV (computer simulator). How to write a scientific article (classroom).



- EXAMS

3 mid-term exams and one remedial exam



Learning activities and methodology

Title Hours ECTS Learning outcomes
Practical classes 12 0.48 1, 2, 6, 7, 9
Discussion of articles 2 0.08 1, 3, 6, 8, 10, 11
Discussion of cases 6 0.24 2, 3, 4, 5, 7, 11
Preparation work / article / simulations 30 1.2 2, 3, 4, 5, 6, 10, 11
Theoretical Classes (Magistral) 50 2 4, 5, 6, 7, 8, 10, 11
Study 103 4.12 5, 6, 7, 10, 11
Computer simulation 4 0.16 2, 4, 6, 8, 11
Seminars 6 0.24 2, 6, 7, 10, 11



- Theory classes


- Seminars: The objective is to reinforce some of the concepts that have been developed in theory classes, through practical exercises.


- Practical classes: these are carried out in the experimental laboratory. Students organize themselves to develop the practical experiences where the students learn how to manipulate and administrate the animals under the professor supervision.


- Computer simulations: Here students carry out virtual experiments through Pharmacology programs aimed at reinforcing certain concepts explained in the theoretical program.


- Self-learning: discussion of cases and articles. Students will have to solve on their own account certain cases proposed by the teaching staff, and that they will have to develop in group. A discussion will be made in common. The work groups will be of maximum 4 students and a minimum of 3. In the case of the discussion of articles, the students will have to prepare the oral presentation on different articles proposed by teachers (group work). The work groups will be of maximum 4 students and a minimum of 3.

The proposed teaching methodology may experience some modifications depending on the restrictions to face-to-face activities enforced by health or University authorities.

Annotation: within the schedule set by the centre or degree programme, 15 minutes of one class will be reserved for students to evaluate their lecturers and their courses or modules through questionnaires.

Assessment

Continuous assessment activities

Title Weight Hours ECTS Learning outcomes
Presentation and discussion article (1) (evaluated during the session) 4 0 0 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11
3 Exams 80% 6 0.24 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11
Drug discovery 4 2 0.08 11
Writing (scientific paper) 4 2 0.08 1, 2, 3, 4, 5, 6, 7, 8, 9, 10
Cases (3) (evaluated during session) 4 0 0 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11
Self learning activity: Neuromuscular junction 4 2 0.08 5, 6

The assessment system consists of tests related to the theoretical / practical part of the program (lectures, seminars and practices) and self-study (cases, works and discussion of articles). Attendance to the practical program is mandatory. If a student misses more than one practice without justification, the practical program will be suspended and they will have to repeat it.

Theoretical-practical evaluation:

1. 3 exams with different evaluable activities

2. 6 Team / individual projects.

This subject does not provide for the single assessment system

* Final note:

  1. 80% corresponding to the average mark of 3 exams + 20% to the average mark of the works.
  2. In order to be able to make the average between the three partials, the student must pass the three partials with at least a 4
  3. In order to pass, the average of the three partials must be at least a 5
  4. To pass the subject, the final grade, calculated as point 1, must be at least 5

Remedial final exams

The remedial exams consist of an independent test for each partial. Students who have failed a partial with less than a 4, that the average of the three partials is lower than 5, or who want to improve the grade of one of the three exams, they can present themselves in the part that suits them.

Not assessable

In the event that a student has not taken any of the partial exams, or any make-up exams, the subject will be considered non-evaluable

Characteristics:

If the mark obtained in the examination of recovery is inferior to the note of the partial one that was tried to surpass, will take into account the highest note.

REPEATERS

The notes of the teamwork are kept for repeatingstudents. In the event that a repeating student wants to improve the grade of any of the teamwork, he can notify the teaching team to include it in the list of students for the specific practice.

Student’s assessment may experiences ome modifications depending on the restrictions to face-to-face activities enforced by health or Universityauthorities

USE OF IA

In this subject, the use of Artificial Intelligence (AI) technologies is allowed as an integral part of the development of the work, provided that the final result reflects a significant contribution by the student in the analysis and personal reflection. The student must clearly identify which parts have been generated with this technology, specify the tools used and include a critical reflection on how these have influenced the process and the final result of the activity. The lack of transparency in the use of AI will be considered a lack of academic honesty and may lead to a penalty in the grade of the activity, or major sanctions in serious cases

Bibliography

- ADAMS, H.R. Veterinary Pharmacology and Therapeutics. Iowa State University Press/Ames, 8ª Ed (2001)

 - BOOTHE, D.M.. Small Animal Clinical Pharmacology and Therapeutics. 1a edició. W.B. Saunders, 2001

 - BAÑOS, JE, FARRE, M. Principios de Farmacologia clínica: bases científicas de la utilización de medicamentos. Ediciones Masson, (2002).

 - BRUNTON LL et al. Goodman and Gilman: Las Bases Farmacológicas de la Terapéutica. Editorial McGraw-Hill Interamericana, 11ª ed., (2006)

 - BOTANA, LM. Farmacologia Veterinaria, (2016) on line:

  http://www.medicapanamericana.com/visorebookv2/ebook/9788498359503#{\"Pagina\":\"Cover\",\"Vista\":\"Indice\",\"Busqueda\":\"\"}

 - BRUNTON LL et al. Goodman and Gilman: Las Bases Farmacológicas de la Terapéutica. Editorial McGraw-Hill Interamericana, 11ª ed., 2006

 - FLOREZ, J, ARMIJO, JA, MEDIAVILLA, A. Farmacología Humana. Barcelona: Elsevier España, 6a Ed (2014).

 - GIGUÈRE S, PRESCOTT SF, BAGGOT JD, WALKER RD & DOWLING PM. Antimicrobial Therapy in Veterinary Medicina. 5th Edition (2013)

 - HILAL-DANDAN, R, BRUNTON, LL. Goodman & Gilman's: Manual of Pharmacology and Therapeutics. New York: Mc-Graw-Hill Interamericana, 2nd Ed (2014).

-  HITNER H, NAGLE B. Introducción a la Farmacología. Editorial Mc-Graw-Hill Interamericana, 5ª ed, (2007)

 - KATZUNG B G, MASTERS SB, TREVOR AJ. Farmacología básica y clínica. Editorial McGraw-Hill Interamericana, 11a ed, 2010

- PLUMB, DC. Plumb's Veterinary Drug Handbook, 9 Ed (2018)

 - RANG ANDDALE. Pharmacology, 9 Ed (2019) 

 - RIVIERE, JE, PAPICH, MG. Veterinary Pharmacology and Therapeutics 9 Ed (2009)

 - Flashcards de Farmacologia bàsica.  Com accedir-hi: entrar a la web de la biblioteca: https://www.uab.cat/biblioteques/ Desprès a revistes digitals i finalment posar: Flashcards de Farmacologia básica (hi ha tb una entrada de Flashcards de Rang&Dales) 

 

 

ALTRES FONTS ONLINE

https://pubmed.ncbi.nlm.nih.gov/

World Wide Science.org

Springer Link

Ref seek

BASE (Bielefeld Academia Search Engine)

ScienceResearch.com

Software

Neuromuscular Pharmacology. Sheffield BioScience programs. 2 Woodgates Mount, North Ferriby, UK (2020).

Rat Cardiovascular System (c). J. Dempster, University of Stratchlyde (1996-2020)

Course groups and languages

The information provided is provisional until November 30. After this date, you will be able to consult the language of each group through this link. To access the information, you will need to enter the course CODE

Type of teaching Group Language Semester Shift
(TE) Theory 1 Catalan/Spanish annual afternoon
(PAUL) Classroom practices 1 Catalan/Spanish annual morning-mixed
(PLAB) Practical laboratories 1 Catalan/Spanish annual morning-mixed
(SEM) Seminars 1 Catalan/Spanish annual morning-mixed
(TE) Theory 2 Catalan/Spanish annual afternoon
(PAUL) Classroom practices 2 Catalan/Spanish annual morning-mixed
(PLAB) Practical laboratories 2 Catalan/Spanish annual morning-mixed
(SEM) Seminars 2 Catalan/Spanish annual morning-mixed
(PAUL) Classroom practices 3 Catalan/Spanish annual morning-mixed
(PLAB) Practical laboratories 3 Catalan/Spanish annual morning-mixed
(SEM) Seminars 3 Catalan/Spanish annual morning-mixed
(PLAB) Practical laboratories 4 Catalan/Spanish annual morning-mixed
(SEM) Seminars 4 Catalan/Spanish annual morning-mixed
(PLAB) Practical laboratories 5 Catalan/Spanish annual morning-mixed
(SEM) Seminars 5 Catalan/Spanish annual morning-mixed
(PLAB) Practical laboratories 6 Catalan/Spanish annual morning-mixed
(SEM) Seminars 6 Catalan/Spanish annual morning-mixed